Area of research
Molecular Biology · Ophthalmology
Research interest
Research interests include Epigenetics and DNA Methylation, Retinal Diseases and Treatments, Vitamin C and Antioxidants Research, and Retinal Development and Disorders.
ADAMTSL2 mutations determine the phenotypic severity in geleophysic dysplasia
Epigenomic regulation by labile iron
Vitamin C sensitizes triple negative breast cancer to PI3K inhibition therapy
Vitamin C regulates Schwann cell myelination by promoting DNA demethylation of pro‐myelinating genes
Magnetic separation of peripheral nerve-resident cells underscores key molecular features of human Schwann cells and fibroblasts: an immunochemical and transcriptomics approach
Whole exome profiling and mutational analysis of Ocular Surface Squamous Neoplasia
Mitochondrial Transfer of the Mutant Human <i>ND6T14484C</i> Gene Causes Visual Loss and Optic Neuropathy
Vitamin C Inhibits Triple-Negative Breast Cancer Metastasis by Affecting the Expression of YAP1 and Synaptopodin 2
Vitamin C supplementation expands the therapeutic window of BETi for triple negative breast cancer
A truncating CLDN9 variant is associated with autosomal recessive nonsyndromic hearing loss
Oscillatory cAMP signaling rapidly alters H3K4 methylation
Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression
Phenotypic and Functional Characteristics of Human Schwann Cells as Revealed by Cell-Based Assays and RNA-SEQ
MPZL2 is a novel gene associated with autosomal recessive nonsyndromic moderate hearing loss
Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells
Human Epicardial Fat Expresses Glucagon-Like Peptide 1 and 2 Receptors Genes
Novel atherogenic pathways from the differential transcriptome analysis of diabetic epicardial adipose tissue
Molecular Characteristics of Conjunctival Melanoma Using Whole-Exome Sequencing
Vitamin C Sensitizes Melanoma to BET Inhibitors
cAMP signaling regulates DNA hydroxymethylation by augmenting the intracellular labile ferrous iron pool
Ascorbate induces apoptosis in melanoma cells by suppressing Clusterin expression
Whole Exome Sequencing of Lacrimal Gland Adenoid Cystic Carcinoma
The epigenetic role of vitamin C in health and disease
Regulation of the Epigenome by Vitamin C
Epigenetic reprogramming of melanoma cells by vitamin C treatment
Human Papilloma Virus Infection Does Not Predict Response to Interferon Therapy in Ocular Surface Squamous Neoplasia
Rare Complement Factor H Variant Associated With Age-Related Macular Degeneration in the Amish
Ascorbate Induces Ten-Eleven Translocation (Tet) Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine
Ascorbate-induced generation of 5-hydroxymethylcytosine is unaffected by varying levels of iron and 2-oxoglutarate