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Lin Shen

Beijing Tongren Hospital · CN
Area of research
Pulmonary and Respiratory Medicine · Oncology
Research interest
Research interests include Gastric Cancer Management and Outcomes, Cancer Immunotherapy and Biomarkers, Esophageal Cancer Research and Treatment, and Colorectal Cancer Treatments and Studies.
h-index
57
citations
18,427
works
499
NIH funding
primary concept
Medicine
email

Recent publications

Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial
The Lancet 2025cited by 93position: lastdoi
First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial
Nature Medicine 2025cited by 76position: firstdoi
Lenvatinib Plus Pembrolizumab and Chemotherapy Versus Chemotherapy in Advanced Metastatic Gastroesophageal Adenocarcinoma: The Phase III, Randomized LEAP-015 Study
Journal of Clinical Oncology 2025cited by 14position: middledoi
Multimodal radiopathomics signature for prediction of response to immunotherapy-based combination therapy in gastric cancer using interpretable machine learning
Cancer Letters 2025cited by 9position: middledoi
Standard: Human gastric organoids
Cell Regeneration 2025cited by 8position: middledoi
Effectiveness, safety, and patterns of use of camrelizumab in advanced esophageal cancer: an individual patient data pooled analysis of 987 patients from three prospective cohort studies
Cancer Immunology Immunotherapy 2025cited by 5position: lastdoi
An integrated prognosis prediction model based on real-word clinical characteristics for immunotherapy in advanced esophageal squamous cell carcinoma
Cancer Immunology Immunotherapy 2025cited by 5position: middledoi
Author Correction: First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial
Nature Medicine 2025cited by 2position: firstdoi
Abstract CT168: EMB-01, an EGFR/cMET bispecific antibody, in metastatic colorectal cancer: Results from an international phase Ib/II study
Cancer Research 2025cited by 2position: firstdoi
Clinical practice guidelines for esophagogastric junction cancer: Upper GI Oncology Summit 2023
Gastric Cancer 2024cited by 19position: middledoi
Efficacy and safety of surufatinib plus toripalimab, a chemotherapy-free regimen, in patients with advanced gastric/gastroesophageal junction adenocarcinoma, esophageal squamous cell carcinoma, or biliary tract cancer
Cancer Immunology Immunotherapy 2024cited by 16position: lastdoi
Results of a phase 1/2 study of MHB088C: A novel B7H3 antibody-drug conjugate (ADC) incorporating a potent DNA topoisomerase I inhibitor in recurrent or metastatic solid tumors.
Journal of Clinical Oncology 2024cited by 14position: firstdoi
LBA60 Phase III study of SHR-1701 versus placebo in combination with chemo as first-line (1L) therapy for HER2-negative gastric/gastroesophageal junction adenocarcinoma (G/GEJA)
Annals of Oncology 2024cited by 11position: lastdoi
Atezolizumab and trastuzumab plus chemotherapy in patients with HER2+ locally advanced resectable gastric cancer or adenocarcinoma of the gastroesophageal junction: A multicenter, randomized, open-label phase II study.
Journal of Clinical Oncology 2024cited by 11position: lastdoi
The METTL3-m6A-YTHDC1-AMIGO2 axis contributes to cell proliferation and migration in esophageal squamous cell carcinoma
Gene 2024cited by 8position: middledoi
Phase I study of <scp>BC001</scp>, a novel fully human immunoglobulin <scp>G1</scp> monoclonal antibody targeting the vascular endothelial growth factor receptor‐2, in advanced solid tumors
Cancer Medicine 2024cited by 4position: lastdoi
Standard: Human gastric cancer organoids
Cell Regeneration 2024cited by 3position: middledoi
872P Safety and efficacy of toripalimab combined with cetuximab in PD-L1 positive untreated recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC): A phase Ib/II study
Annals of Oncology 2024cited by 2position: middledoi
DCQNet: Collaborative Camouflaged Object Detection Using Cross-Sample and Cross-Scale Network
2024cited by 0position: lastdoi
Pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma: interim analyses from the phase 3 KEYNOTE-811 randomised placebo-controlled trial
The Lancet 2023cited by 446position: middledoi
Sintilimab Plus Chemotherapy for Unresectable Gastric or Gastroesophageal Junction Cancer
JAMA 2023cited by 346position: middledoi
Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment for advanced or metastatic oesophageal squamous cell carcinoma (RATIONALE-306): a global, randomised, placebo-controlled, phase 3 study
The Lancet Oncology 2023cited by 282position: middledoi
Safety and antitumour activity of cadonilimab, an anti-PD-1/CTLA-4 bispecific antibody, for patients with advanced solid tumours (COMPASSION-03): a multicentre, open-label, phase 1b/2 trial
The Lancet Oncology 2023cited by 190position: middledoi
Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study
The Lancet Oncology 2023cited by 83position: middledoi
Non-invasive CT imaging biomarker to predict immunotherapy response in gastric cancer: a multicenter study
Journal for ImmunoTherapy of Cancer 2023cited by 45position: middledoi
Multilevel proteomic analyses reveal molecular diversity between diffuse-type and intestinal-type gastric cancer
Nature Communications 2023cited by 43position: middledoi
LBA79 GEMSTONE-303: Prespecified progression-free survival (PFS) and overall survival (OS) final analyses of a phase III study of sugemalimab plus chemotherapy vs placebo plus chemotherapy in treatment-naïve advanced gastric or gastroesophageal junction (G/GEJ) adenocarcinoma
Annals of Oncology 2023cited by 31position: lastdoi
Zolbetuximab + CAPOX in 1L claudin-18.2+ (CLDN18.2+)/HER2− locally advanced (LA) or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary phase 3 results from GLOW.
Journal of Clinical Oncology 2023cited by 30position: middledoi
Larotrectinib long-term efficacy and safety in adult patients (pts) with tropomyosin receptor kinase (TRK) fusion cancer.
Journal of Clinical Oncology 2023cited by 15position: lastdoi
LBA78 Overall survival of perioperative or postoperative adjuvant oxaliplatin with S-1 versus adjuvant oxaliplatin with capecitabine in locally advanced gastric or gastro-oesophageal junction adenocarcinoma undergoing D2 gastrectomy: An updated analysis of RESOLVE trial
Annals of Oncology 2023cited by 13position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Kohei Shitara · Kindai University9 papers (2021–2023)Yuxian Bai · Harbin Medical University9 papers (2012–2023)Eric Van Cutsem · KU Leuven9 papers (2012–2023)Jianming Xu · University of Technology Sydney7 papers (2015–2024)Rui‐Hua Xu · Henan Medical University7 papers (2017–2023)Yelena Y. Janjigian · Cancer Clinic7 papers (2021–2023)Jifang Gong · Peking University6 papers (2020–2024)Pooja Bhagia · Merck & Co., Inc., Rahway, NJ, USA (United States)6 papers (2021–2023)Yanqiao Zhang · Zhejiang Provincial People's Hospital6 papers (2020–2025)Hyun Cheol Chung · Harbin Medical University6 papers (2012–2023)Tianshu Liu · Sun Yat-sen University6 papers (2019–2022)Josep Tabernero · Medical Research Network5 papers (2021–2023)Jaffer A. Ajani · The University of Texas MD Anderson Cancer Center5 papers (2012–2023)Hongming Pan · Sir Run Run Shaw Hospital5 papers (2012–2022)Sara Lonardi · Istituto Oncologico Veneto5 papers (2021–2023)Lucjan Wyrwicz · Wojskowy Instytut Medyczny5 papers (2021–2023)Akihito Kawazoe · National Cancer Research Institute5 papers (2021–2023)Yongqian Shu · Suzhou Municipal Hospital5 papers (2019–2023)Shukui Qin · People's Liberation Army No. 150 Hospital5 papers (2021–2023)Nong Xu · Hangzhou First People's Hospital4 papers (2015–2022)