Area of research
Infectious Diseases · Molecular Biology
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, High-pressure geophysics and materials, Ion channel regulation and function, and RNA Research and Splicing.
Structural basis for the substrate recognition and transport mechanism of the human y<sup>+</sup>LAT1-4F2hc transporter complex.
Molecular insights into species-specific ACE2 recognition of coronavirus HKU5.
Structural basis for substrate recognition mechanism of human SLC26A7.
Structures of human γδ T cell receptor-CD3 complex.
The complete assembly of human LAT1-4F2hc complex provides insights into its regulation, function and localisation.
Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.
Filament structures unveil the dynamic organization of human acetyl-CoA carboxylase.
Chitosan/PLGA-based tissue engineered nerve grafts with SKP-SC-EVs enhance sciatic nerve regeneration in dogs through miR-30b-5p-mediated regulation of axon growth
Angiogenesis-promoting effect of SKP-SC-EVs-derived miRNA-30a-5p in peripheral nerve regeneration by targeting LIF and ANGPT2
Comprehensive structural analysis reveals broad-spectrum neutralizing antibodies against SARS-CoV-2 Omicron variants.
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2.
The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis.
Structure of the cytoplasmic ring of the <i>Xenopus laevis</i> nuclear pore complex.
Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex.
Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses.
Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states.
Cryo-EM structure of the nuclear ring from Xenopus laevis nuclear pore complex.
Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD
Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD.
AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2
Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2.
Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies
ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker
A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols.
Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cryo-EM structure of human Wntless in complex with Wnt3a
Cryo-EM structure of human Wntless in complex with Wnt3a.
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.