Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, Genomics and Phylogenetic Studies, RNA modifications and cancer, and Epigenetics and DNA Methylation.
Identification of Compound Heterozygous CYP11A1 Variants via Reanalysis of Clinical Sequencing Data.
Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation.
Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis.
The cost and cost trajectory of genome sequencing and bioinformatics analysis for Indigenous children with suspected rare diseases.
Evaluating Language Models for Biomedical Fact-Checking: A Benchmark Dataset for Cancer Variant Interpretation Verification
A nuclear TRiC/CCT chaperonin assembles meiotic HORMAD proteins into chromosome axes competent for crossing over.
Proteomics and personalized PDX models identify treatment for a progressive malignancy within an actionable timeframe.
The Genome Sequence of the Hemlock Woolly Adelgid, Adelges tsugae Annand 1924.
The genome sequence of the hemlock woolly adelgid,
<i>Adelges tsugae</i>
Annand 1924
Long-read sequencing of an advanced cancer cohort resolves rearrangements, unravels haplotypes, and reveals methylation landscapes.
AI-based histopathology image analysis reveals a distinct subset of endometrial cancers.
Whole genome and transcriptome integrated analyses guide clinical care of pediatric poor prognosis cancers.
A Deep Learning Approach for the Identification of the Molecular Subtypes of Pancreatic Ductal Adenocarcinoma Based on Whole Slide Pathology Images
VOLTA: an enVironment-aware cOntrastive ceLl represenTation leArning for histopathology.
The benefit of a complete reference genome for cancer structural variant analysis
Canadian COVID-19 host genetics cohort replicates known severity associations.
Enhancing clinical genomic accuracy with panelGC: a novel metric and tool for quantifying and monitoring GC biases in hybridization capture panel sequencing.
Exploration of Germline Correlates and Risk of Immune-Related Adverse Events in Advanced Cancer Patients Treated with Immune Checkpoint Inhibitors.
Mitofusin 2 Variant Presenting With a Phenotype of Multiple System Atrophy of Cerebellar Subtype.
Establishing association between HLA-C*04:01 and severe COVID-19.
"I Just Assumed This Was Already Being Done": Canadian Patient Preferences for Enhanced Data Sharing for Precision Oncology.
Correction: Titmuss et al. Immune Activation Following Irbesartan Treatment in a Colorectal Cancer Patient: A Case Study. <i>Int. J. Mol. Sci.</i> 2023, <i>24</i>, 5869.
A second update on mapping the human genetic architecture of COVID-19.
CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase.
Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq.
NCBP2 and TFRC are novel prognostic biomarkers in oral squamous cell carcinoma.
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration.
Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers.
Defining the heterogeneity of unbalanced structural variation underlying breast cancer susceptibility by nanopore genome sequencing.
macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma.