Area of research
Molecular Biology
Research interest
Research focused on Cell biology and Epigenetics, with related work in Chromatin, RNA splicing, Haematopoiesis. Notable publications include 'UTX condensation underlies its tumour-suppressive activity', 'Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis', and 'Regulation of Pluripotency and Self- Renewal of ESCs through Epigenetic- Threshold Modulation and mRNA Pruning'.
Dissecting the biophysics and biology of intrinsically disordered proteins
UTX condensation underlies its tumour-suppressive activity
Subcellular Localization of miRNAs and Implications in Cellular Homeostasis
Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis
Control of Hematopoietic Stem and Progenitor Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity
Specific inhibition of DPY30 activity by ASH2L-derived peptides suppresses blood cancer cell growth
A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells
Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer
Dpy30 is critical for maintaining the identity and function of adult hematopoietic stem cells
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors
The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells
Regulation of Pluripotency and Self- Renewal of ESCs through Epigenetic- Threshold Modulation and mRNA Pruning
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