Area of research
Ophthalmology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Retinal Diseases and Treatments, Retinal Imaging and Analysis, Retinal and Optic Conditions, and Ophthalmology and Visual Impairment Studies.
Novel drug development for geographic atrophy
Edridge Green Lecture 2022-demystifying clinical trials and regulatory approvals in drug development.
Electrodiagnostic Tests as Potential Efficacy Endpoints in Clinical Trials of Novel Pharmacological Therapies for Acquired Retinal Disorders.
Subretinal drusenoid deposits, age-related macular degeneration, and cardiovascular disease
Associations of presenting visual acuity with morphological changes on OCT in neovascular age-related macular degeneration: PRECISE Study Report 2.
Baseline characteristics of eyes with early residual fluid post loading phase of aflibercept therapy in neovascular AMD: PRECISE study report 3.
Subretinal transient hyporeflectivity in neovascular age-related macular degeneration and its response to a loading phase of aflibercept: PRECISE report 4.
Imaging Modalities for Assessing the Vascular Component of Diabetic Retinal Disease: Review and Consensus for an Updated Staging System
Factors That Can Prolong Ocular Treatment Duration in Age-Related Macular Degeneration.
Quantitative Autofluorescence in Non-Neovascular Age Related Macular Degeneration.
A Multi-Modal AI-Driven Cohort Selection Tool to Predict Suboptimal Non-Responders to Aflibercept Loading-Phase for Neovascular Age-Related Macular Degeneration: PRECISE Study Report 1.
Perspectives from clinical trials: is geographic atrophy one disease?
Intraretinal Microvascular Abnormalities and Venous Beading Have Different Genetic Profiles in Caucasian Patients with Non-Proliferative Diabetic Retinopathy.
Re: Teo et al.: Geographic atrophy phenotypes in subjects of different ethnicity: Asia-Pacific Ocular Imaging Society Work Group Report 3 (Ophthalmol Retina. 2023;7:593-604).
Machine learning OCT predictors of progression from intermediate age-related macular degeneration to geographic atrophy and vision loss.
HORNBILL: a phase I/IIa trial examining the safety, tolerability and early response of BI 764524 in patients with diabetic retinopathy and diabetic macular ischaemia-rationale, study design and protocol.
Standard threshold laser versus subthreshold micropulse laser for adults with diabetic macular oedema: the DIAMONDS non-inferiority RCT.
Diabetic Macular Ischemia: Influence of Optical Coherence Tomography Angiography Parameters on Changes in Functional Outcomes Over One Year
Evaluation of a New Model of Care for People with Complications of Diabetic Retinopathy: The EMERALD Study.
Looking Ahead: Visual and Anatomical Endpoints in Future Trials of Diabetic Macular Ischemia.
Endpoints: The Beginning of a New Treatment?
Multimodal imaging interpreted by graders to detect re-activation of diabetic eye disease in previously treated patients: the EMERALD diagnostic accuracy study.
Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration: Classification of Atrophy Meeting Report 4.
Efficacy and safety of subthreshold micropulse laser compared with threshold conventional laser in central serous chorioretinopathy.
Aflibercept Reduces Retinal Hemorrhages and Intravitreal Microvascular Abnormalities But Not Venous Beading: Secondary Analysis of the CLARITY Study.
Radiotherapy for neovascular age-related macular degeneration
Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration
Impact of Diabetic Retinopathy on Sleep, Mood, and Quality of Life.
A pilot prospective study of 577-nm yellow subthreshold micropulse laser treatment with two different power settings for acute central serous chorioretinopathy.
Randomised trial of wide-field guided PRP for diabetic macular oedema treated with ranibizumab.