Area of research
Virology · Immunology
Research interest
Research interests include HIV Research and Treatment, Immune Cell Function and Interaction, T-cell and B-cell Immunology, and Hepatitis C virus research.
Metabolic dysregulation of lymphocytes in autoimmune diseases
Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques
Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection
Spleen fibroblastic reticular cell-derived acetylcholine promotes lipid metabolism to drive autoreactive B cell responses
Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth
Double knockout of Akt2 and AMPK accentuates high fat diet-induced cardiac anomalies through a cGAS-STING-mediated mechanism
Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection
Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance
Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques
Derivation and Characterization of Pathogenic Transmitted/Founder Molecular Clones from Simian Immunodeficiency Virus SIVsmE660 and SIVmac251 following Mucosal Infection
Identification, Molecular Cloning, and Analysis of Full-Length Hepatitis C Virus Transmitted/Founder Genotypes 1, 3, and 4
A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility
Early Low-Titer Neutralizing Antibodies Impede HIV-1 Replication and Select for Virus Escape
Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome Sequencing
Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones