Area of research
Physiology · Molecular Biology
Research interest
Research focused on Telomerase and Telomere, with related work in Telomerase reverse transcriptase, Enhancer, Epigenomics. Notable publications include 'Telomerase directly regulates NF-κB-dependent transcription', 'H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions', and 'VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma'.
High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma
Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities
H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer
Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent <i>CCNE1</i> and <i>IGF2</i> enhancer hijacking in primary gastric adenocarcinoma
<i>VHL</i> Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity
Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene
Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression
High-throughput genotyping of CRISPR/Cas9-mediated mutants using fluorescent PCR-capillary gel electrophoresis
Quantitative assessment of telomerase components in cancer cell lines
Loss of miR-200b promotes invasion via activating the Kindlin-2/integrin β1/AKT pathway in esophageal squamous cell carcinoma: An E-cadherin-independent mechanism
Expansion and Homing of Umbilical Cord Blood Hematopoietic Stem and Progenitor Cells for Clinical Transplantation
Network based analyses of gene expression profile of LCN2 overexpression in esophageal squamous cell carcinoma
Telomerase directly regulates NF-κB-dependent transcription
The Role of Telomere Biology in Cancer