Area of research
Organic Chemistry · Spectroscopy
Research interest
Research interests include Analytical Chemistry and Chromatography, Synthesis and Biological Evaluation, Synthesis and biological activity, and Cancer-related molecular mechanisms research.
Integrated network pharmacology and comprehensive bioinformatics identifying the mechanisms and molecular targets of Jieyu Anshen Granules for treating comorbidity with Alzheimer's disease and depression
Novel naftopidil derivatives containing methyl phenylacetate and their blocking effects on α1D/1A-adrenoreceptor subtypes
Pharmaceutical evaluation of naftopidil enantiomers: Rat functional assays in vitro and estrogen/androgen induced rat benign prostatic hyperplasia model in vivo
Poor and enantioselective bioavailability of naftopidil enantiomers is due to extensive and stereoselective metabolism in rat liver
Novel naftopidil-related derivatives and their biological effects as alpha1-adrenoceptors antagonists and antiproliferative agents
TF/FVIIa/PAR2 promotes cell proliferation and migration via PKCα and ERK-dependent c-Jun/AP-1 pathway in colon cancer cell line SW620
Involvement of PKCα activation in TF/VIIa/PAR2-induced proliferation, migration, and survival of colon cancer cell SW620