Area of research
Molecular Biology · Hepatology · organoid drug screen
Research interest
Research interests include Advanced biosensing and bioanalysis techniques, Hepatocellular Carcinoma Treatment and Prognosis, RNA modifications and cancer, and Ferroptosis and cancer prognosis.
CLIM-TIME links genetic cancer drivers to immune landscapes.
Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1<sup>+</sup> TAMs.
Author response: Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs
Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs
Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs
Deciphering the role of the MALT1-RC3H1 axis in regulating GPX4 protein stability.
DYRK1A-TGF-β signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma
Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs and CD8+ T cells
Reply to Mishima et al.: MALT1 modulates GPX4 expression by regulating its stability.
Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs and CD8+ T cells
Author response: Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs and CD8+ T cells
Author response: Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs and CD8+ T cells
Precision treatment in advanced hepatocellular carcinoma
Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy
Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy
Dual Inhibition of CDK4/6 and XPO1 Induces Senescence With Acquired Vulnerability to CRBN-Based PROTAC Drugs
Dual Inhibition of CDK4/6 and XPO1 Induces Senescence With Acquired Vulnerability to CRBN-Based PROTAC Drugs
SSRI antidepressant citalopram reverses the Warburg effect to inhibit hepatocellular carcinoma by directly targeting GLUT1
Deciphering the role of the MALT1–RC3H1 axis in regulating GPX4 protein stability
Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1
<sup>+</sup>
TAMs
Evolving therapeutic landscape of advanced hepatocellular carcinoma.
Feedback activation of EGFR/wild-type RAS signaling axis limits KRAS<sup>G12D</sup> inhibitor efficacy in KRAS<sup>G12D</sup>-mutated colorectal cancer.
Identification of a Novel Ferroptosis Inducer with Dual Modulatory Effects on GPX4 Activity and Stability
Combating inconsistent evaluation of intra-tumor immune status by a novel transcriptomic signature in hepatocellular carcinoma.
Evolving therapeutic landscape of advanced hepatocellular carcinoma
A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer.
Long noncoding RNA LHFPL3-AS2 suppresses metastasis of non-small cell lung cancer by interacting with SFPQ to regulate TXNIP expression
Integrative analysis of CRISPR screening data uncovers new opportunities for optimizing cancer immunotherapy
EGFR blockade confers sensitivity to cabozantinib in hepatocellular carcinoma.
Author response: A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer