Area of research
Molecular Biology · Oncology
Research interest
Research interests include Histone Deacetylase Inhibitors Research, Peptidase Inhibition and Analysis, Protein Degradation and Inhibitors, and Ion channel regulation and function.
Discovery of selective HDAC6 inhibitors driven by artificial intelligence and molecular dynamics simulation approaches
RadioPharm: the database of radiopharmaceuticals
A Novel Compound <scp>QO</scp>‐83 Alleviates Acute and Chronic Epileptic Seizures in Rodents by Modulating <scp>K<sub>V</sub>7</scp> Channel Activity
Discovery of E0199: A novel compound targeting both peripheral NaV and KV7 channels to alleviate neuropathic pain
Discovery of Potent Selective HDAC6 Inhibitors with 5-Phenyl-1<i>H</i>-indole Fragment: Virtual Screening, Rational Design, and Biological Evaluation
Effectiveness and safety of auricular acupuncture on adjuvant analgesia in patients with total knee arthroplasty: a randomized sham-controlled trial
Discovery of a novel compound E0199 that simultaneously targets both peripheral NaV and KV7 ion channels to alleviate neuropathic pain
INTEDE 2.0: the metabolic roadmap of drugs
Discovery of selective HDAC6 inhibitors based on a multi-layer virtual screening strategy
Design, Synthesis, and Biological Evaluation of Benzo[B]Thiophene 1,1-Dioxide (BTP) Derivatives
Design, Synthesis, and biological evaluation of HDAC6 inhibitors based on Cap modification strategy
Do biological activities of selective histone deacetylase 6 (<scp>HDAC6</scp>) inhibitors rely on the modification of cap group?
Mechanism of drug resistance of BVDV induced by F224S mutation in RdRp: A case study of VP32947
VARIDT 2.0: structural variability of drug transporter
Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain
Discovery of Potent EGFR Inhibitors With 6-Arylureido-4-anilinoquinazoline Derivatives
Comparison of the Inhibitory Binding Modes Between the Planar Fascaplysin and Its Nonplanar Tetrahydro-β-carboline Analogs in CDK4
Synthesis and Biological Evaluation of HDAC Inhibitors With a Novel Zinc Binding Group
Cholesterol, 24-Hydroxycholesterol, and 27-Hydroxycholesterol as Surrogate Biomarkers in Cerebrospinal Fluid in Mild Cognitive Impairment and Alzheimer’s Disease: A Meta-Analysis
Probing the mechanism of plasma protein adsorption on Au and Ag nanoparticles with FT-IR spectroscopy
Tumor cell targeted delivery by specific peptide-modified mesoporous silica nanoparticles