Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, Melanoma and MAPK Pathways, Cancer Immunotherapy and Biomarkers, and Bladder and Urothelial Cancer Treatments.
TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling.
Senolysis Enabled by Senescent Cell‐Sensitive Bioorthogonal Tetrazine Ligation
Selective Elimination of Senescent Cancer Cells by Galacto-Modified PROTACs
Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach.
Evaluation of the antitumor effect of neoantigen peptide vaccines derived from the translatome of lung cancer
Functional significance of cholesterol metabolism in cancer: from threat to treatment
Bioorthogonal PROTAC Prodrugs Enabled by On-Target Activation
Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways.
Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach
An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes
Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study.
Building bioorthogonal click-release capable artificial receptors on cancer cell surface for imaging, drug targeting and delivery
Deterministic evolution and stringent selection during pre-neoplasia
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
A CRISPR/Cas9-Engineered <i>ARID1A</i> -Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation
A CRISPR/Cas9-Engineered <i>ARID1A</i>-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation.
Cell of Origin Influences Pancreatic Cancer Subtype.
Selection of metastasis competent subclones in the tumour interior.
Spatial patterns of tumour growth impact clonal diversification: computational modelling and evidence in the TRACERx Renal study
Pervasive chromosomal instability and karyotype order in tumour evolution
Pervasive chromosomal instability and karyotype order in tumour evolution.
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity.
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
Evaluation of Two Primer Sets for Amplification of Comammox Nitrospira amoA Genes in Wetland Soils
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal
Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal
The prognostic value of preoperative neutrophil-to-lymphocyte ratio in patients with upper tract urothelial carcinoma
Tracking the Evolution of Non–Small-Cell Lung Cancer