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Lei Jiang

Southwestern Medical Center · US
Area of research
Cancer Research · Physiology
Research interest
Research focused on Mitochondrion and Glutamine, with related work in Pentose phosphate pathway, Glutaminolysis, Cell biology. Notable publications include 'Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport', 'Reductive carboxylation supports redox homeostasis during anchorage-independent growth', and 'A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth'.
h-index
citations
3,015
works
13
NIH funding
primary concept
email

Recent publications

Distinct adipose progenitor cells emerging with age drive active adipogenesis
Science 2025cited by 37position: middledoi
FASN deficiency induces a cytosol-to-mitochondria citrate flux to mitigate detachment-induced oxidative stress
Cell Reports 2023cited by 16position: lastdoi
An updated HACOR score for predicting the failure of noninvasive ventilation: a multicenter prospective observational study
Critical Care 2022cited by 81position: middledoi
The regulation of long non-coding RNA 00958 (LINC00958) for oral squamous cell carcinoma (OSCC) cells death through absent in melanoma 2 (AIM2) depending on microRNA-4306 and Sirtuin1 (SIRT1) in vitro
Bioengineered 2021cited by 35position: firstdoi
Chronic cold exposure enhances glucose oxidation in brown adipose tissue
EMBO Reports 2020cited by 51position: lastdoi
Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans
Cell Reports 2019cited by 121position: middledoi
Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism
Nature Cell Biology 2017cited by 324position: middledoi
Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis
Cell Metabolism 2017cited by 277position: middledoi
Reductive carboxylation supports redox homeostasis during anchorage-independent growth
Nature 2016cited by 595position: firstdoi
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling
Nature Cell Biology 2015cited by 283position: middledoi
Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
Molecular Cell 2014cited by 678position: middledoi
A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth
Molecular Cell 2014cited by 379position: middledoi
Lysine Acetylation Activates 6-Phosphogluconate Dehydrogenase to Promote Tumor Growth
Molecular Cell 2014cited by 138position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Ralph J. DeBerardinis · Children's Medical Center6 papers (2014–2023)Jared Rutter · University of Utah5 papers (2014–2020)Qiong Wang · Southwestern Medical Center4 papers (2016–2025)Chendong Yang · Children's Medical Center3 papers (2014–2019)Wenting Dai · Ministry of Education of the People's Republic of China2 papers (2023–2025) · 2 papers (2020–2025)Bookyung Ko · Southwestern Medical Center2 papers (2014–2019)Miao Ren · Suzhou Research Institute2 papers (2017–2017)John C. Schell · University of Utah2 papers (2014–2017)James E. Cox · University of Utah2 papers (2017–2017)Claire Bensard · University of California San Diego2 papers (2017–2017)Kristofor A. Olson · Colorectal Surgical Associates2 papers (2014–2017)Zhichao Wang · Jilin University2 papers (2020–2023)Yutian Zhao · University of California, Los Angeles1 papers (2025–2025)Jianxin Xie · Shihezi University1 papers (2014–2014)Nicola Longo · Center for Human Genetics1 papers (2017–2017)Marzia Pasquali · ARUP Laboratories (United States)1 papers (2017–2017) · 1 papers (2016–2016)Nick V. Grishin · Southwestern Medical Center1 papers (2019–2019)Seth J. Parker · Pacific Centre for Reproductive Medicine1 papers (2016–2016)