Area of research
Microbiology · Pharmacology
Research interest
Research focused on Stereochemistry and Prime (order theory), with related work in Neuropathology, PINK1, Plant biochemistry. Notable publications include 'Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure', 'Mutant Alpha-Synuclein Causes Age-Dependent Neuropathology in Monkey Brain', and 'Co-editing PINK1 and DJ-1 Genes Via Adeno-Associated Virus-Delivered CRISPR/Cas9 System in Adult Monkey Brain Elicits Classical Parkinsonian Phenotype'.
Aspidosperma-type bisindole alkaloids from Melodinus suaveolens and their antiproliferative activities
Gelselegine-gelsedine type bisindoles as well as the units from Gelsemium elegans with promoting proliferation of oral mucosa fibroblast cells
Rearranged and enantiomeric alkaloids from Cephalotaxus sinensis
Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable off-target mutations in human HSCs
Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure
Enantiomeric Cephalotaxus alkaloids from seeds of Cephalotaxus oliveri
Co-editing PINK1 and DJ-1 Genes Via Adeno-Associated Virus-Delivered CRISPR/Cas9 System in Adult Monkey Brain Elicits Classical Parkinsonian Phenotype
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft'
Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from <i>Bousigonia angustifolia</i>
Cage-Monoterpenoid Quinoline Alkaloids with Neurite Growth Promoting Effects from the Fruits of <i>Melodinus yunnanensis</i>
Tabernabovines A–C: Three Monoterpenoid Indole Alkaloids from the Leaves of <i>Tabernaemontana bovina</i>
Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of <i>Tabernaemontana bovina</i>
Novel monoterpenoid indole alkaloids from Melodinus yunnanensis
Polycyclic monoterpenoid indole alkaloids from Alstonia rostrata and their reticulate derivation
Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina
Microarray expression profile analysis of aberrant long non-coding RNAs in esophageal squamous cell carcinoma
Two key biogenetic intermediates of Cephalotaxus alkaloids from Cephalotaxus oliveri and C. lanceolata
Mutant Alpha-Synuclein Causes Age-Dependent Neuropathology in Monkey Brain
Colored Sticky Traps to Selectively Survey Thrips in Cowpea Ecosystem
Effects of warming on root diameter, distribution, and longevity in an alpine meadow