Area of research
Oncology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include CAR-T cell therapy research, Monoclonal and Polyclonal Antibodies Research, CRISPR and Genetic Engineering, and HER2/EGFR in Cancer Research.
Multiscale proteomic modeling reveals protein networks driving Alzheimer’s disease pathogenesis
PLXNB1 and other signaling drives a pathologic astrocyte state contributing to cognitive decline in Alzheimer’s Disease
CRISPR-engineered deletion of <i>POGZ</i> alters transcription factor binding at promoters of genes involved in synaptic signaling
MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease
Convergent coexpression of autism-associated genes suggests some novel risk genes may not be detectable in large-scale genetic studies
Multi-omic profiling of the developing human cerebral cortex at the single cell level
Convergent and non-additive impact of schizophrenia risk genes in human neurons
Convergent coexpression of autism associated genes suggests some novel risk genes may not be detectable in large-scale genetic studies
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
Puerarin ameliorated pressure overload-induced cardiac hypertrophy in ovariectomized rats through activation of the PPARα/PGC-1 pathway
MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells
Molecular Networks and Key Regulators of the Dysregulated Neuronal System in Alzheimer’s Disease
Mitochondrial dysfunction and mitophagy defect triggered by heterozygous <i>GBA</i> mutations
Efficient electrochemical detection of cancer cells on in situ surface-functionalized MoS<sub>2</sub>nanosheets
Association between HLA-DQB1 alleles and susceptibility to coronary artery disease in Southern Han Chinese
Blood-based lung cancer biomarkers identified through proteomic discovery in cancer tissues, cell lines and conditioned medium
iPSC-Derived Dopamine Neurons Reveal Differences between Monozygotic Twins Discordant for Parkinson’s Disease
IGF-1 Activates a Cilium-Localized Noncanonical Gβγ Signaling Pathway that Regulates Cell-Cycle Progression