Area of research
Endocrinology, Diabetes and Metabolism · Epidemiology
Research interest
Research interests include Diabetes, Cardiovascular Risks, and Lipoproteins, Liver Disease Diagnosis and Treatment, Genetic Associations and Epidemiology, and Cardiovascular Health and Disease Prevention.
Intensive blood pressure control and risks of cognitive outcomes in patients with new-onset orthostatic hypotension.
Associations of general and central obesity with risk of premature mortality among Chinese adults: A nationwide prospective cohort study.
Blood Pressure Levels and Outcomes in Type 2 Diabetes
Interaction between physical activity and deficit-based frailty on all-cause mortality in older adults: a prospective study of five population-based cohorts.
Identification of gut microbiota causally associated with aging and longevity and mediation roles of the cerebrospinal fluid proteins: proteomic genetic evidence from Mendelian randomization.
Longitudinal exposure to non-HDL-C and cardiovascular events, all-cause mortality in type 2 diabetes: A post hoc analysis of the ACCORD trial.
Comparison of Different Intermittent Fasting Patterns or Different Extents of Calorie Restriction for Weight Loss and Metabolic Improvement in Adults: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
Age-specific effects of hemoglobin A1c, blood pressure, and cholesterol levels on incident cardiovascular diseases among adults with diabetes in China: a 10-year prospective cohort study.
Intensive Blood-Pressure Control in Patients with Type 2 Diabetes.
Association of body roundness index with cardiovascular disease and all‐cause mortality among Chinese adults
Association of body roundness index with cardiovascular disease and all-cause mortality among Chinese adults.
The Effect of SGLT2 Inhibition on Brain-related Phenotypes and Aging: A Drug Target Mendelian Randomization Study.
Oxidative stress and antioxidant therapeutic mechanisms
Elucidating the heterogeneity of prediabetes through subphenotyping with a two-dimensional tree structure
Circulating short-chain and branched short-chain fatty acids and the risk of incident type 2 diabetes: findings from the 4C study
Serum Medium-Chain Fatty Acids and the Risk of Incident Diabetes: Findings From the 4C Study.
Multivariate genome-wide analyses of insulin resistance unravel novel loci and therapeutic targets for cardiometabolic health.
Circulating short-chain and branched short-chain fatty acids and the risk of incident type 2 diabetes: findings from the 4C study.
Breakthrough in human induced pluripotent stem cell research of a functional cure for type 1 diabetes.
Effects of Intensive Systolic Blood Pressure Control on Kidney Outcomes in Patients With and Without CKD: A Post Hoc Analysis of SPRINT and ACCORD-BP Trials.
Intensive systolic blood pressure control in patients with or without worsening renal function.
Effect of insulin sensitivity, insulin secretion, and beta cell function on the remission of type 2 diabetes: A post hoc analysis of the IDEATE trial.
Socioeconomic and mental health inequalities in global burden of type 2 diabetes: Evidence from the Global Burden of Disease Study 2021.
Phenotyping obesity through a two-dimensional tree structure reveals cardiometabolic heterogeneity
Associations of general and central obesity with risk of premature mortality among Chinese adults: A nationwide prospective cohort study
Multivariate genome-wide analyses of insulin resistance phenotypes unravel novel loci and therapeutic targets for cardiometabolic health and longevity
Neither VitD nor VitD binding protein or VitD receptor has causal effect on cancers: a Mendelian randomization study.
Identifying PDAP1 as a Biological Target on Human Longevity: Integration of Mendelian Randomization, Cohort, and Cell Experiments Validation Study.
Heterogeneous blood pressure treatment effects on cognitive decline in type 2 diabetes: A machine learning analysis of a randomized clinical trial.