Area of research
Endocrinology, Diabetes and Metabolism · Genetics
Research interest
Research interests include Thyroid Disorders and Treatments, Diabetes and associated disorders, Sexual Differentiation and Disorders, and Genetic Associations and Epidemiology.
Large-scale screening and functional study of <i>DUOXA2</i> variant in 599 Chinese patients with congenital hypothyroidism
Large-scale screening and functional study of DUOXA2 variant in 599 Chinese patients with congenital hypothyroidism.
Clinical Outcomes of Congenital Hypothyroidism Due to <i>DUOX2</i> Biallelic Mutations after Levothyroxine Withdrawal.
Identification of Eukaryotic Translation Initiation Factor 4B as a Novel Candidate Gene for Congenital Hypothyroidism.
Deficiency of the HGF/Met pathway leads to thyroid dysgenesis by impeding late thyroid expansion.
The effects of disturbance on hypothalamus-pituitary-thyroid axis in zebrafish larvae after exposure to polyvinyl alcohol
<i>TSHR</i> Variant Screening and Phenotype Analysis in 367 Chinese Patients With Congenital Hypothyroidism.
<i>TAF1</i> is needed for the proliferation and maturation of thyroid follicle cells via Notch signaling.
Myeloid cells interact with a subset of thyrocytes to promote their migration and follicle formation through NF-κB.
Pathogenic variations in <i>MAML2</i> and <i>MAMLD1</i> contribute to congenital hypothyroidism due to dyshormonogenesis by regulating the Notch signalling pathway.
Lymphocyte infiltration and thyrocyte destruction are driven by stromal and immune cell components in Hashimoto's thyroiditis.
The mutation screening in candidate genes related to thyroid dysgenesis by targeted next-generation sequencing panel in the Chinese congenital hypothyroidism.
Detection of <i>BRAF</i> V600E in Fine-Needle Aspiration Samples of Thyroid Nodules by Droplet Digital PCR.
Mutation Screening and Functional Study of <i>SLC26A4</i> in Chinese Patients with Congenital Hypothyroidism
Correlation of DUOX2 residual enzymatic activity with phenotype in congenital hypothyroidism caused by biallelic DUOX2 defects.
Genetic Manipulation on Zebrafish duox Recapitulate the Clinical Manifestations of Congenital Hypothyroidism.
Molecular and clinical genetics of the transcription factor GLIS3 in Chinese congenital hypothyroidism.
Three-dimensional microscopy and image fusion reconstruction analysis of the thyroid gland during morphogenesis.
Subchronic exposure to concentrated ambient PM2.5 perturbs gut and lung microbiota as well as metabolic profiles in mice
Genetic Study in a Large Cohort Supported Different Pathogenesis of Graves’ Disease and Hashimoto’s Hypothyroidism
Genetic Study in a Large Cohort Supported Different Pathogenesis of Graves' Disease and Hashimoto's Hypothyroidism.
The TPO mutation screening and genotype-phenotype analysis in 230 Chinese patients with congenital hypothyroidism.
Urinary Iodine and Genetic Predisposition to Hashimoto's Thyroiditis in a Chinese Han Population: A Case-Control Study.
Bisphenol A exposure and risk of thyroid nodules in Chinese women: A case-control study.
Mutation screening of the TSHR gene in 220 Chinese patients with congenital hypothyroidism.
Assessment of Molecular Subtypes in Thyrotoxic Periodic Paralysis and Graves Disease Among Chinese Han Adults: A Population-Based Genome-Wide Association Study.
Uterus globulin associated protein 1 (UGRP1) is a potential marker of progression of Graves' disease into hypothyroidism
A Weighted Genetic Risk Score Using Known Susceptibility Variants to Predict Graves Disease Risk.
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci