Area of research
Immunology · Cell Biology
Research interest
Research focused on Genetics and Exome sequencing, with related work in Single-nucleotide polymorphism, Genome-wide association study, Meta-analysis. Notable publications include 'Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity', 'Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians', and 'Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease'.
Therapeutic potential of MCC950, a specific inhibitor of NLRP3 inflammasome
A Large-Scale, Exome-Wide Association Study of Han Chinese Women Identifies Three Novel Loci Predisposing to Breast Cancer
Identification of pathways and genes associated with cerebral palsy
Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity
Exome-wide association study identifies four novel loci for systemic lupus erythematosus in Han Chinese population
Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease
A Genetic Variant rs1020760at <i>NFKB1</i> is Associated with Clinical Features of Psoriasis Vulgaris in a Han Chinese Population
Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis
Discovery of a novel genetic susceptibility locus on X chromosome for systemic lupus erythematosus
Sequencing-based approach identified three new susceptibility loci for psoriasis
Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne
Exome sequencing identifies <i>SLC17A9</i> pathogenic gene in two Chinese pedigrees with disseminated superficial actinic porokeratosis
A large-scale screen for coding variants predisposing to psoriasis
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis
Association analyses identifying two common susceptibility loci shared by psoriasis and systemic lupus erythematosus in the Chinese Han population
Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians
Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation
Exome sequencing identifies MVK mutations in disseminated superficial actinic porokeratosis