Area of research
Immunology · Molecular Biology
Research interest
Research interests include interferon and immune responses, Inflammasome and immune disorders, Autophagy in Disease and Therapy, and Invertebrate Immune Response Mechanisms.
Palmitoylation of GPX4 via the targetable ZDHHC8 determines ferroptosis sensitivity and antitumor immunity
ABHD8 antagonizes inflammation by facilitating chaperone-mediated autophagy-mediated degradation of NLRP3
Phase-separated nucleocapsid protein of SARS-CoV-2 suppresses cGAS-DNA recognition by disrupting cGAS-G3BP1 complex
Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to facilitate innate immune response
Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy
Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome
Selective autophagy controls the stability of TBK1 via NEDD4 to balance host defense
Selective autophagy controls the stability of transcription factor IRF3 to balance type I interferon production and immune suppression
USP38 Couples Histone Ubiquitination and Methylation via KDM5B to Resolve Inflammation
LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I