Area of research
Cancer Research · Biological Psychiatry
Research interest
Research focused on Glioma and Adeno-associated virus, with related work in Temozolomide, Cancer research, HMGB1. Notable publications include 'BBB-crossing adeno-associated virus vector: An excellent gene delivery tool for CNS disease treatment', 'LincRNA-p21 knockdown reversed tumor-associated macrophages function by promoting MDM2 to antagonize* p53 activation and alleviate breast cancer development', and 'Upregulation of miR-216a exerts neuroprotective effects against ischemic injury through negatively regulating JAK2/STAT3-involved apoptosis and inflammatory pathways'.
Role of TREM2 in immune and neurological diseases: Structure, function, and implications
The targeting of DAPK1 with miR‐190a‐3p promotes autophagy in trophoblast cells
Functional mechanism and clinical implications of miR-141 in human cancers
BBB-crossing adeno-associated virus vector: An excellent gene delivery tool for CNS disease treatment
Challenges in adeno-associated virus-based treatment of central nervous system diseases through systemic injection
HMGB1 is a Potential and Challenging Therapeutic Target for Parkinson’s Disease
LincRNA-p21 knockdown reversed tumor-associated macrophages function by promoting MDM2 to antagonize* p53 activation and alleviate breast cancer development
HMGB1 A box protects neurons by potently inhibiting both microglia and T cell-mediated inflammation in a mouse Parkinson’s disease model
Long Non-coding RNA EPIC1 Promotes Cell Proliferation and Motility and Drug Resistance in Glioma
Fibroblast transdifferentiation promotes conversion of M1 macrophages and replenishment of cardiac resident macrophages following cardiac injury in mice
MicroRNA-365 suppressed cell proliferation and migration via targeting PAX6 in glioblastoma.
PubMed 2019cited by 14position: middle
Upregulation of miR-216a exerts neuroprotective effects against ischemic injury through negatively regulating JAK2/STAT3-involved apoptosis and inflammatory pathways
Angiotensin II enhances the acetylation and release of HMGB1 in RAW264.7 macrophage
Cdc20 overexpression is involved in temozolomide-resistant glioma cells with epithelial-mesenchymal transition
Overexpression of Transforming Acidic Coiled Coil‑Containing Protein 3 Reflects Malignant Characteristics and Poor Prognosis of Glioma
Comparative Analysis of Matrix Metalloproteinase Family Members Reveals That MMP9 Predicts Survival and Response to Temozolomide in Patients with Primary Glioblastoma