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David M. Davies

Guy's Hospital · GB
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Area of research
Immunology · Oncology
Research interest
Research interests include CAR-T cell therapy research, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, and T-cell and B-cell Immunology.
h-index
24
citations
2,735
works
55
NIH funding
primary concept
email

Recent publications

Granzyme B-activated IL18 potentiates αβ and γδ CAR T cell immunotherapy in a tumor-dependent manner
Molecular Therapy 2024cited by 30position: middledoi
Solid tumor immunotherapy using NKG2D-based adaptor CAR T cells
Cell Reports Medicine 2024cited by 17position: middledoi
Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study
Journal for ImmunoTherapy of Cancer 2023cited by 45position: middledoi
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors
Cell Reports Medicine 2021cited by 138position: middledoi
Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors
Cell Reports Medicine 2021cited by 53position: middledoi
TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer
Cell Reports Medicine 2021cited by 40position: middledoi
CAR T-Cells Targeting the Integrin αvβ6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies
Cancers 2019cited by 197position: middledoi
The role of the interleukin (IL)-6/IL-6 receptor axis in cancer
Biochemical Society Transactions 2018cited by 130position: middledoi
A phase I trial of T4 CAR T-cell immunotherapy in head and neck squamous cancer (HNSCC).
Journal of Clinical Oncology 2018cited by 46position: middledoi
Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells
Molecular Therapy 2017cited by 75position: middledoi
CAR T-cell immunotherapy of MET-expressing malignant mesothelioma
OncoImmunology 2017cited by 74position: middledoi
Intracavitary ‘T4 immunotherapy’ of malignant mesothelioma using pan-ErbB re-targeted CAR T-cells
Cancer Letters 2017cited by 59position: middledoi
Preclinical In Vivo Modeling of Cytokine Release Syndrome Induced by ErbB-Retargeted Human T Cells: Identifying a Window of Therapeutic Opportunity?
The Journal of Immunology 2013cited by 128position: middledoi
Synergistic Chemoimmunotherapy of Epithelial Ovarian Cancer Using ErbB-Retargeted T Cells Combined with Carboplatin
The Journal of Immunology 2013cited by 60position: middledoi
Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling
Journal of Clinical Immunology 2012cited by 483position: middledoi
Flexible Targeting of ErbB Dimers That Drive Tumorigenesis by Using Genetically Engineered T Cells
Molecular Medicine 2012cited by 111position: firstdoi

Grants

SBIR Phase I: Semiconductor: Micro Solid Immersion Lens for Small Mobile Optical Disc Drive
NSF0539911$100,0002006–2006PIRePORTER
Dispersion of Pseudomonas Aeruginosa Biofilms
NSF0321672$150,0002003–2006PIRePORTER
Continental Volcaniclastics, Volcan De Fuego, Guatemala
NSF7812365$29,9331978–1980PIRePORTER
Continental Volcanic Sediments, Guatemala
NSF7420040$64,3001974–1979PIRePORTER

Frequent collaborators

John Maher · Guy's Hospital13 papers (2012–2024)Ana C. Parente Pereira · King's College London8 papers (2012–2019)Lynsey M. Whilding · Oxford BioMedica (United Kingdom)7 papers (2013–2021)Scott Wilkie · Mission Hospital4 papers (2012–2013)May CI van Schalkwyk · King's College London4 papers (2012–2018)Daniel Larcombe-Young · King's College - North Carolina4 papers (2021–2024)Sjoukje J. C. van der Stegen · Chan Zuckerberg Initiative (United States)4 papers (2012–2013)Daniela Achkova · King's College London4 papers (2017–2021)Tomasz Zabinski · Translational Therapeutics (United States)3 papers (2017–2019)Natalie Woodman · University College London3 papers (2017–2021)Roseanna M. Petrovic · Memorial Sloan Kettering Cancer Center3 papers (2013–2017)James Spicer · King's College London3 papers (2017–2018)Anna Schurich · King's College - North Carolina3 papers (2021–2024)Caroline Hull · Guy's Hospital3 papers (2021–2024)Sadaf Ghaem‐Maghami · Imperial College Healthcare NHS Trust3 papers (2013–2017)S. Burbridge · Guy's Hospital2 papers (2012–2012) · 2 papers (2012–2012) · 2 papers (2012–2013)Mustafa Yassin Taher · Taibah University2 papers (2018–2021)Jana Obajdin · King's College London2 papers (2021–2024)
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