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Linghua Zhang

South China Agricultural University · CN
Area of research
Immunology · Hematology
Research interest
Research focused on Pichia pastoris and Clostridium butyricum, with related work in Immune system, CpG Oligodeoxynucleotide, Gene. Notable publications include 'Native and Engineered Probiotics: Promising Agents against Related Systemic and Intestinal Diseases', 'Effect of cooperation of chaperones and gene dosage on the expression of porcine PGLYRP-1 in Pichia pastoris', and 'Controlling AOX1 promoter strength in Pichia pastoris by manipulating poly (dA:dT) tracts'.
h-index
citations
291
works
22
NIH funding
primary concept
email

Recent publications

Identification of prevalent Feline Calicivirus strains and novel antiviral efficacy of CpG49 stimulus in Feline Calicivirus-infected cats
International Journal of Biological Macromolecules 2025cited by 3position: lastdoi
A standardized set of pNX vectors for enhanced soluble expression of recombinant proteins in E. coli using small fusion tags
Microbial Cell Factories 2025cited by 1position: middledoi
Native and Engineered Probiotics: Promising Agents against Related Systemic and Intestinal Diseases
International Journal of Molecular Sciences 2022cited by 47position: lastdoi
LACpG10-HL Functions Effectively in Antibiotic-Free and Healthy Husbandry by Improving the Innate Immunity
International Journal of Molecular Sciences 2022cited by 1position: lastdoi
Overexpression of pEGF improved the gut protective function of Clostridium butyricum partly through STAT3 signal pathway
Applied Microbiology and Biotechnology 2021cited by 21position: lastdoi
Intestinal guard: Human CXCL17 modulates protective response against mycotoxins and CXCL17-mimetic peptides development
Biochemical Pharmacology 2021cited by 10position: lastdoi
YBX has functional roles in CpG-ODN against cold stress and bacterial infection of Misgurnus anguillicaudatus
Fish & Shellfish Immunology 2021cited by 8position: lastdoi
Protective effects of Clostridium butyricum against oxidative stress induced by food processing and lipid-derived aldehydes in Caco-2 cells
Applied Microbiology and Biotechnology 2020cited by 20position: lastdoi
Co-expressing GroEL–GroES, Ssa1–Sis1 and Bip–PDI chaperones for enhanced intracellular production and partial-wall breaking improved stability of porcine growth hormone
Microbial Cell Factories 2020cited by 16position: lastdoi
Identification of RBP4 from bighead carp (Hypophthalmichthys nobilis) / silver carp (Hypophthalmichthys molitrix) and effects of CpG ODN on RBP4 expression under A. hydrophila challenge
Fish & Shellfish Immunology 2020cited by 7position: lastdoi
Molecular cloning, characterization and expression profiles of Annexin family (ANXA1~A6) in yellow catfish (Pelteobagrus fulvidraco) and ANX regulation by CpG ODN responding to bacterial infection
Fish & Shellfish Immunology 2020cited by 7position: lastdoi
Effects of porcine IL-17B and IL-17E against intestinal pathogenic microorganism
Molecular Immunology 2019cited by 7position: lastdoi
Recombinant plasmids containing CpG with porcine host defense peptides (PR-39/pBD-1) modulates the innate and adaptive intestinal immune responses (including maternal-derived) in piglets
International Immunopharmacology 2019cited by 5position: lastdoi
Modulating the 3’ end-DNA and the fermentation process for enhanced production and biological activity of porcine interferon-gamma
PLoS ONE 2019cited by 3position: lastdoi
Controlling AOX1 promoter strength in Pichia pastoris by manipulating poly (dA:dT) tracts
Scientific Reports 2018cited by 35position: lastdoi
Effect of cooperation of chaperones and gene dosage on the expression of porcine PGLYRP-1 in Pichia pastoris
Applied Microbiology and Biotechnology 2016cited by 41position: lastdoi
CRIP1, a novel immune-related protein, activated by Enterococcus faecalis in porcine gastrointestinal epithelial cells
Gene 2016cited by 20position: lastdoi
CpG oligodeoxynucleotide protect neonatal piglets from challenge with the enterotoxigenic E. coli
Veterinary Immunology and Immunopathology 2014cited by 7position: lastdoi
Immunization of Aged Pigs with Attenuated Pseudorabies Virus Vaccine Combined with CpG Oligodeoxynucleotide Restores Defective Th1 Immune Responses
PLoS ONE 2013cited by 14position: lastdoi
Innate defense regulator peptide synergizes with CpG ODN for enhanced innate intestinal immune responses in neonate piglets
International Immunopharmacology 2012cited by 12position: lastdoi
Age-related impaired Th1 responses to PRV vaccine in vivo in aged pigs
Molecular Immunology 2012cited by 6position: lastdoi
Protective effect of different immune route of CpG-ODN on piglets
Guangdong nongye kexue 2012cited by 0position: first

Grants

No grants ingested yet.

Frequent collaborators

Feiping Ming · South China Agricultural University15 papers (2013–2025)Haiming Cai · South China Agricultural University14 papers (2012–2021)Miaopeng Ma · South China Agricultural University13 papers (2012–2022)Junhao Jia · South China Agricultural University10 papers (2019–2021)Min Zeng · Guangzhou University of Chinese Medicine9 papers (2016–2021)Qianyi Liang · Guangzhou University of Chinese Medicine8 papers (2019–2021)Zengjue Zhao · South China Agricultural University7 papers (2020–2022)Haokun Shen · South China Agricultural University7 papers (2020–2022)Ding Cao · South China Agricultural University6 papers (2012–2021)Peijing Zhao · South China Agricultural University6 papers (2019–2020)Qin Fan · South China Agricultural University6 papers (2019–2022)Jun Yang · South China Agricultural University5 papers (2012–2018)Jiayi Li · Central South University of Forestry and Technology5 papers (2019–2021)Rongxiao He · South China Agricultural University4 papers (2021–2022)Juqing Shi · South China Agricultural University4 papers (2012–2020)Pinpin Chu · South China Agricultural University4 papers (2013–2021)Chao‐Yuan Huang · Hebei Medical University4 papers (2013–2019)Jiaoqing Li · South China Agricultural University4 papers (2019–2020)Guanhua Gan · South China Agricultural University4 papers (2021–2022)Saixiang Feng · South China Agricultural University4 papers (2021–2022)