Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, Epigenetics and DNA Methylation, and Cancer-related molecular mechanisms research.
CRISPR–Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames
Regulation of the Proliferation of Diabetic Vascular Endothelial Cells by Degrading Endothelial Cell Functional Genes with QKI‐7
Exposure to Polycyclic Aromatic Hydrocarbons and Accelerated DNA Methylation Aging
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting
Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library
Partitioning heritability by functional annotation using genome-wide association summary statistics
Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR
Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens
Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases
EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
Chromatin marks identify critical cell types for fine mapping complex trait variants