Area of research
Molecular Biology · Hematology
Research interest
Research focused on DNA methylation and Pancreatic cancer, with related work in Cancer research, Epigenetics, Induced pluripotent stem cell. Notable publications include 'DNA methylation presents distinct binding sites for human transcription factors', 'Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation', and 'Small-molecule–directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells'.
Structural basis for nucleolin recognition of <i>MYC</i> promoter G-quadruplex
Two-stage CD8+ CAR T-cell differentiation in patients with large B-cell lymphoma
Ref‐1 redox activity regulates retinal neovascularization by modulating transcriptional activation of <scp>HIF</scp> ‐1α
Age-adjusted cut-off values of natriuretic peptides for right ventricular dysfunction in acute pulmonary embolism: Post-hoc analysis from CURES
Sex- and age-associated factors drive the pathophysiology of MASLD
Performance of the Simplified Pulmonary Embolism Severity Index in predicting 30-day mortality after acute pulmonary embolism: Validation from a large-scale cohort
A T Cell‐Engaging Tumor Organoid Platform for Pancreatic Cancer Immunotherapy
Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population
Aspartyl-tRNA synthetase 2 orchestrates iron-sulfur metabolism in hematopoietic stem cells via fine-tuning alternative RNA splicing
Discovery and Biological Characterization of PRMT5:MEP50 Protein–Protein Interaction Inhibitors
LMWHs dosage and outcomes in acute pulmonary embolism with renal insufficiency, an analysis from a large real-world study
ADGRG1 enriches for functional human hematopoietic stem cells following ex vivo expansion–induced mitochondrial oxidative stress
An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine
The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice
Spleen Tyrosine Kinase–Mediated Autophagy Is Required for Epithelial–Mesenchymal Plasticity and Metastasis in Breast Cancer
The role of GLI-SOX2 signaling axis for gemcitabine resistance in pancreatic cancer
Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation
Small-molecule–directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells
Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression
DNA methylation presents distinct binding sites for human transcription factors