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Ya Zhao

Guangzhou University of Chinese Medicine · CN
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Area of research
Molecular Biology · Pharmacology
Research interest
Research focused on Multidrug resistance-associated protein 2 and Transporter, with related work in Efflux, Radix (gastropod), Traditional medicine. Notable publications include 'Polysaccharide from vinegar baked radix bupleuri as efficient solubilizer for water-insoluble drugs of Chinese medicine', 'The Arabidopsis receptor-like kinase WAKL4 limits cadmium uptake via phosphorylation and degradation of NRAMP1 transporter', and 'Saikosaponin b2 enhances the hepatotargeting effect of anticancer drugs through inhibition of multidrug resistance-associated drug transporters'.
h-index
citations
396
works
31
NIH funding
primary concept
email

Recent publications

Nano-pectic polysaccharide from vinegar-baked Radix Bupleuri enhances methotrexate efficacy against hepatocellular carcinoma via BCRP and MRP2 downregulation
International Journal of Biological Macromolecules 2025cited by 2position: middledoi
Anti-Hepatitis B Virus Activities of a Polysaccharide from Vinegar-Baked Radix Bupleuri in Vitro: Evidences for its Mechanisms of Action
Journal of Polymers and the Environment 2025cited by 0position: firstdoi
Guben-Qushi-Huayu formula and calycosin improve epidermal barrier function in psoriasis by inhibiting small proline-rich protein 1A
Phytomedicine 2025cited by 0position: middledoi
The Arabidopsis receptor-like kinase WAKL4 limits cadmium uptake via phosphorylation and degradation of NRAMP1 transporter
Nature Communications 2024cited by 38position: middledoi
Xiaoyaosan promotes neurotransmitter transmission and alleviates CUMS-induced depression by regulating the expression of Oct1 and Oct3 in astrocytes of the prefrontal cortex
Journal of Ethnopharmacology 2024cited by 12position: middledoi
A novel pectin polysaccharide from vinegar-baked Radix Bupleuri absorbed by microfold cells in the form of nanoparticles
International Journal of Biological Macromolecules 2024cited by 9position: firstdoi
An inulin-type polysaccharide from Atractylodis Macrocephalae Rhizoma can relieve psoriasis
International Journal of Biological Macromolecules 2024cited by 7position: middledoi
Ultrasound-Assisted Extraction of <i>Atractylodes chinensis</i> (DC.) Koidz. Polysaccharides and the Synergistic Antigastric Cancer Effect in Combination with Oxaliplatin
ACS Omega 2024cited by 6position: middledoi
Comparison of structure and the synergistic anti-hepatocellular carcinoma effect of three polysaccharides from vinegar-baked Radix Bupleuri
International Journal of Biological Macromolecules 2024cited by 4position: middledoi
Increased Abnormal Erythrocytes Caused by Spleen Filtration Deficiency Provide a Hypoxic Environment for the Occurrence of Psoriasis
Experimental Dermatology 2024cited by 1position: firstdoi
Polysaccharides derived from alkali-extracted vinegar-baked Radix Bupleuri suppress hyperimmune T lymphocytes and ameliorate skin graft rejection
Journal of Traditional and Complementary Medicine 2024cited by 0position: firstdoi
Comparative Study on Anti-Inflammatory Effect of Polysaccharides from Vinegar-Baked <i>Radix Bupleuri</i> Using Different Methods
ACS Omega 2023cited by 11position: middledoi
Citric Acid Enhances the Activities of Astilbin on Psoriasis via Down-Regulation of <i>P</i>-Glycoprotein
Molecular Pharmaceutics 2023cited by 8position: middledoi
Size, surface charge and flexibility of vinegar-baked Radix Bupleuri polysaccharide affecting the immune response
Arabian Journal of Chemistry 2022cited by 14position: middledoi
Vinegar-baked Radix Bupleuri enhances the liver-targeting effect of rhein on liver injury rats by regulating transporters
Journal of Pharmacy and Pharmacology 2022cited by 13position: firstdoi
Polysaccharides of vinegar-baked radix bupleuri promote the hepatic targeting effect of oxymatrine by regulating the protein expression of HNF4α, Mrp2, and OCT1
Journal of Ethnopharmacology 2020cited by 21position: middledoi
Polysaccharide from vinegar baked radix bupleuri as efficient solubilizer for water-insoluble drugs of Chinese medicine
Carbohydrate Polymers 2019cited by 44position: firstdoi
Saikosaponin b2 enhances the hepatotargeting effect of anticancer drugs through inhibition of multidrug resistance-associated drug transporters
Life Sciences 2019cited by 24position: firstdoi
Platycodon grandiflorus enhances the effect of DDP against lung cancer by down regulating PI3K/Akt signaling pathway
Biomedicine & Pharmacotherapy 2019cited by 22position: middledoi
Interactions Between Emodin and Efflux Transporters on Rat Enterocyte by a Validated Ussing Chamber Technique
Frontiers in Pharmacology 2018cited by 15position: middledoi
Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters
Oncotarget 2017cited by 18position: middledoi
Immunomodulatory activities of phlorizin metabolites in lipopolysaccharide-stimulated RAW264.7 cells
Biomedicine & Pharmacotherapy 2017cited by 13position: firstdoi
Clerosterol from vinegar-baked radix bupleuri modifies drug transport
Oncotarget 2017cited by 9position: firstdoi
Smilax glabra Rhizoma affects the pharmacokinetics and tissue distribution of methotrexate by increasing the P-glycoprotein mRNA expression in rats after oral administration
Molecular Medicine Reports 2017cited by 4position: middledoi
Effects of compatibility of radix aconiti carmichaeli and pinelia ternate on pharmacokinetic of 9 aconitum alkaloids in normal and model rat plasma
Drug Metabolism and Pharmacokinetics 2017cited by 0position: firstdoi
Vinegar amount in the process affected the components of vinegar-baked Radix Bupleuri and its hepatoprotective effect
BMC Complementary and Alternative Medicine 2016cited by 23position: firstdoi
Systematic Analysis of Absorbed Anti-Inflammatory Constituents and Metabolites of Sarcandra glabra in Rat Plasma Using Ultra-High-Pressure Liquid Chromatography Coupled with Linear Trap Quadrupole Orbitrap Mass Spectrometry
PLoS ONE 2016cited by 15position: middledoi
<i>Dendrobium officinale</i> Prevents Early Complications in Streptozotocin‐Induced Diabetic Rats
Evidence-based Complementary and Alternative Medicine 2016cited by 13position: middledoi
A new coumarin isolated from <i>Sarcandra glabra</i> as potential anti-inflammatory agent
Natural Product Research 2015cited by 21position: middledoi
Simultaneous quantification of 17 bioactive constituents in Sarcandra glabra by liquid chromatography-electrospray ionisation-mass spectrometry
Analytical Methods 2014cited by 13position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Ruizhi Zhao · Guangzhou University of Chinese Medicine21 papers (2016–2025)Yayun Wu · Guangzhou University of Chinese Medicine17 papers (2016–2025)Lijuan Liu · First Affiliated Hospital of Xi'an Jiaotong University5 papers (2017–2022)Chuanjian Lu · Guangzhou University of Chinese Medicine4 papers (2023–2025)Lijuan Liu · Guangzhou University of Chinese Medicine4 papers (2022–2024)Xiaoshuang Wang · Sun Yat-sen University4 papers (2022–2024)Jin Zhao · Guangzhou University of Chinese Medicine3 papers (2014–2016)Xiao‐Ping Lai · Guangzhou University of Chinese Medicine3 papers (2013–2017)Shigui Deng · Guangzhou University of Chinese Medicine3 papers (2017–2024)Qiaohong Hu · University of Iowa3 papers (2019–2025)Lijuan Liu · Tianjin Chengjian University3 papers (2024–2025)Limin Feng · Guangzhou University of Chinese Medicine3 papers (2017–2019)Minghui Han · Guangzhou University of Chinese Medicine3 papers (2022–2025)Xing Zeng · Guangzhou University of Chinese Medicine2 papers (2014–2017)Shaozhen Hou · Guangzhou University of Chinese Medicine2 papers (2016–2017)Runyue Huang · Utrecht University2 papers (2014–2015)Xing Zeng · McGill University Health Centre2 papers (2015–2016)Ni Wei · Guangzhou University of Chinese Medicine2 papers (2023–2024)Jinqiu Wang · Ningbo University2 papers (2019–2022)Li‐Juan Liu · Guangzhou University of Chinese Medicine2 papers (2020–2024)
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