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Jérôme Guitton

Université Claude Bernard Lyon 1 · FR
Area of research
Toxicology · Molecular Biology
Research interest
Research focused on Forensic toxicology and Cancer research, with related work in Chromatography, Effector, Dynamin. Notable publications include 'Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling', 'A stemness-related ZEB1–MSRB3 axis governs cellular pliancy and breast cancer genome stability', and 'Vitreous humor analysis for the detection of xenobiotics in forensic toxicology: a review'.
h-index
citations
1,602
works
30
NIH funding
primary concept
email

Recent publications

A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity
Cell Death and Disease 2024cited by 22position: middledoi
Cholesterol biosynthetic pathway induces cellular senescence through ERRα
npj Aging 2024cited by 20position: middledoi
Alteration of ribosome function upon 5-fluorouracil treatment favors cancer cell drug-tolerance
Nature Communications 2022cited by 55position: middledoi
A novel view on an old drug, 5-fluorouracil: an unexpected RNA modifier with intriguing impact on cancer cell fate
NAR Cancer 2021cited by 73position: middledoi
Issues and limitations of available biomarkers for fluoropyrimidine-based chemotherapy toxicity, a narrative review of the literature
ESMO Open 2021cited by 47position: middledoi
Cross-Validation of a Multiplex LC-MS/MS Method for Assaying mAbs Plasma Levels in Patients with Cancer: A GPCO-UNICANCER Study
Pharmaceuticals 2021cited by 27position: middledoi
Analysis of Pembrolizumab in Human Plasma by LC-MS/HRMS. Method Validation and Comparison with Elisa
Biomedicines 2021cited by 18position: middledoi
Quantification of nivolumab in human plasma by LC-MS/HRMS and LC-MS/MS, comparison with ELISA
Talanta 2020cited by 40position: lastdoi
Human Poisoning from Poisonous Higher Fungi: Focus on Analytical Toxicology and Case Reports in Forensic Toxicology
Pharmaceuticals 2020cited by 33position: middledoi
Intra-individual Pharmacokinetic Variability of Intravenous Busulfan in Hematopoietic Stem Cell-Transplanted Children
Clinical Pharmacokinetics 2020cited by 31position: middledoi
Development and validation of a method for quantification of human insulin and its synthetic analogues in plasma and post-mortem sera by LC-MS/HRMS
Talanta 2020cited by 27position: lastdoi
Study of intracellular anabolism of 5-fluorouracil and incorporation in nucleic acids based on an LC-HRMS method
Journal of Pharmaceutical Analysis 2020cited by 26position: lastdoi
Is insulin intoxication still the perfect crime? Analysis and interpretation of postmortem insulin: review and perspectives in forensic toxicology
Critical Reviews in Toxicology 2020cited by 24position: lastdoi
Impact of Interleukin-6 on Drug-Metabolizing Enzymes and Transporters in Intestinal Cells
The AAPS Journal 2019cited by 27position: middledoi
Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints
Cancer Research 2018cited by 67position: middledoi
Esophageal cancer cells resistant to T-DM1 display alterations in cell adhesion and the prostaglandin pathway
Oncotarget 2018cited by 28position: middledoi
A stemness-related ZEB1–MSRB3 axis governs cellular pliancy and breast cancer genome stability
Nature Medicine 2017cited by 177position: middledoi
A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival
Nature Communications 2017cited by 47position: middledoi
(<i>E</i>)‐1,1,4,4‐Tetramethyl‐2‐tetrazene (TMTZ): A Prospective Alternative to Hydrazines in Rocket Propulsion
Chemistry - A European Journal 2017cited by 29position: middledoi
Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution
Oncotarget 2016cited by 74position: middledoi
Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress
PLoS Genetics 2016cited by 53position: middledoi
Vitreous humor analysis for the detection of xenobiotics in forensic toxicology: a review
Forensic Toxicology 2015cited by 127position: lastdoi
State of the art in bile analysis in forensic toxicology
Forensic Science International 2015cited by 56position: middledoi
Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication
PLoS ONE 2015cited by 34position: middledoi
Should busulfan therapeutic range be narrowed in pediatrics? Experience from a large cohort of hematopoietic stem cell transplant children
Bone Marrow Transplantation 2015cited by 31position: middledoi
Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling
Science 2014cited by 207position: middledoi
Fully validated assay for the quantification of endogenous nucleoside mono- and triphosphates using online extraction coupled with liquid chromatography–tandem mass spectrometry
Analytical and Bioanalytical Chemistry 2014cited by 81position: lastdoi
Screening approach by ultra-high performance liquid chromatography–tandem mass spectrometry for the blood quantification of thirty-four toxic principles of plant origin. Application to forensic toxicology
Journal of Chromatography B 2014cited by 60position: middledoi
A validated method for quantifying hypoglycin A in whole blood by UHPLC–HRMS/MS
Journal of Chromatography B 2014cited by 29position: middledoi
Ecotoxicological risk assessment linked to the discharge by hospitals of bio-accumulative pharmaceuticals into aquatic media: The case of mitotane
Chemosphere 2013cited by 32position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Christelle Machon · Université Claude Bernard Lyon 110 papers (2014–2024)Laurent Fanton · Université Claude Bernard Lyon 16 papers (2014–2020) · 6 papers (2014–2020)Nathalie Cartiser · Université Claude Bernard Lyon 14 papers (2015–2020) · 4 papers (2015–2020)Léa Payen · Université Claude Bernard Lyon 13 papers (2016–2019) · 3 papers (2020–2021) · 3 papers (2020–2021) · 3 papers (2020–2021) · 3 papers (2020–2021) · 3 papers (2014–2020)Michaël Philippe · Université Claude Bernard Lyon 12 papers (2015–2020)Charles Dumontet · Clinica Universidad de Navarra2 papers (2014–2018)Frédéric Catez · Université Claude Bernard Lyon 12 papers (2020–2021) · 2 papers (2014–2014)Jean‐Jacques Diaz · Université Claude Bernard Lyon 12 papers (2020–2021)Nathalie Bleyzac · Université Claude Bernard Lyon 12 papers (2015–2020) · 2 papers (2019–2020)Audrey Griveau · Université Claude Bernard Lyon 12 papers (2016–2024)David Bernard · Labex Corail2 papers (2016–2024)