Area of research
Molecular Biology · Immunology
Research interest
Research interests include Mast cells and histamine, Receptor Mechanisms and Signaling, Chemical Synthesis and Analysis, and Olfactory and Sensory Function Studies.
Progress on the development of Class A GPCR‐biased ligands
The stimulation of <scp>TH2</scp> cells results in increased <scp>IL</scp>‐5 and <scp>IL</scp>‐13 production via the <scp>H<sub>4</sub></scp> receptor
Dual Piperidine-Based Histamine H<sub>3</sub> and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain
Data from Phosphatidylserine Synthase PTDSS1 Shapes the Tumor Lipidome to Maintain Tumor-Promoting Inflammation
Increased Remyelination and Proregenerative Microglia Under Siponimod Therapy in Mechanistic Models
Histamine Activates Human Eosinophils via H2R and H4R Predominantly in Atopic Dermatitis Patients
Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H<sub>3</sub> and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties
Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent
Alkyl derivatives of 1,3,5-triazine as histamine H4 receptor ligands
Polypharmacology by Design: A Medicinal Chemist’s Perspective on Multitargeting Compounds
Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies
Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H<sub>3</sub>R Antagonism for Neurodegenerative Diseases
An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms
Human basophil chemotaxis and activation are regulated via the histamine H4 receptor
International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors
Studies on molecular properties prediction and histamine H3 receptor affinities of novel ligands with uracil-based motifs
Luciferase Reporter Gene Assay on Human, Murine and Rat Histamine H4 Receptor Orthologs: Correlations and Discrepancies between Distal and Proximal Readouts
Chapter 3 Histamine Metabolism
Chapter 2 Histamine H<sub>4</sub> Receptor Ligands
DOGS: Reaction-Driven de novo Design of Bioactive Compounds