Area of research
Nephrology · Molecular Biology
Research interest
Research focused on Autophagy and Inflammasome, with related work in Microvesicles, Podocyte, Allosteric regulation. Notable publications include 'Structural basis of GPBAR activation and bile acid recognition', 'JAK/STAT pathway promotes the progression of diabetic kidney disease via autophagy in podocytes', and 'Andrade-Oliveira Salvianolic Acid B Modulates Caspase-1–Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via Nrf2 Pathway'.
A molecular mechanism of UDCA engagement with GPBAR and subsequent G protein interaction revealed by scattered alanine scanning
JAK/STAT pathway promotes the progression of diabetic kidney disease via autophagy in podocytes
Integrated Fecal Microbiome and Serum Metabolomics Analysis Reveals Abnormal Changes in Rats with Immunoglobulin A Nephropathy and the Intervention Effect of Zhen Wu Tang
Structural basis of GPBAR activation and bile acid recognition
Andrade-Oliveira Salvianolic Acid B Modulates Caspase-1–Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via Nrf2 Pathway
Salvianolic acid B attenuates epithelial-mesenchymal transition in renal fibrosis rats through activating Sirt1-mediated autophagy
Zhen-Wu-Tang Protects IgA Nephropathy in Rats by Regulating Exosomes to Inhibit NF-κB/NLRP3 Pathway
Protective role of Astragaloside <scp>IV</scp> in chronic glomerulonephritis by activating autophagy through <scp>PI3K</scp>/<scp>AKT</scp>/<scp>AS160</scp> pathway
Structural basis of bile acid receptor activation and Gs coupling
Renoprotective effects of artemisinin and hydroxychloroquine combination therapy on IgA nephropathy via suppressing NF-κB signaling and NLRP3 inflammasome activation by exosomes in rats
Zhen-wu-tang ameliorates membranous nephropathy rats through inhibiting NF-κB pathway and NLRP3 inflammasome
Paeoniflorin Inhibits Mesangial Cell Proliferation and Inflammatory Response in Rats With Mesangial Proliferative Glomerulonephritis Through PI3K/AKT/GSK-3β Pathway
<i>Cordyceps militaris</i> polysaccharides exerted protective effects on diabetic nephropathy in mice <i>via</i> regulation of autophagy
Immunosuppressive effect of artemisinin and hydroxychloroquine combination therapy on IgA nephropathy via regulating the differentiation of CD4+ T cell subsets in rats
Zhen-wu-tang protects against podocyte injury in rats with IgA nephropathy via PPARγ/NF-κB pathway
Immunosuppressive effects of hydroxychloroquine and artemisinin combination therapy via the nuclear factor‑κB signaling pathway in lupus nephritis mice
Zhen-wu-tang attenuates Adriamycin-induced nephropathy via regulating AQP2 and miR-92b
Paeoniflorin ameliorates Adriamycin-induced nephrotic syndrome through the PPARγ/ANGPTL4 pathway in vivo and vitro
Effect of Maxing Shigan Tang on H1N1 Influenza A Virus-Associated Acute Lung Injury in Mice