Area of research
Computational Theory and Mathematics · Biochemistry
Research interest
Research focused on Apoptosis and Autophagy, with related work in Reactive oxygen species, Triptolide, Oxidative stress. Notable publications include 'Synthesis, characterization and antitumor properties of selenium nanoparticles coupling with ferulic acid', 'Recent advances in the pharmacological applications and liver toxicity of triptolide', and 'Farrerol Directly Targets GSK-3 β to Activate Nrf2-ARE Pathway and Protect EA.hy926 Cells against Oxidative Stress-Induced Injuries'.
<i>In silico</i> design of novel potential isonicotinamide-based glycogen synthase kinase-3β (GSK-3β) inhibitors: 3D-QSAR, molecular docking, molecular dynamics simulation and ADMET studies
Comparative study on interactions of phillyrin and phillygenol with lysozyme: Spectroscopy, differential scanning calorimetry and molecular modeling approaches
Protective effect of astragaloside IV against zinc oxide nanoparticles induced human neuroblastoma SH-SY5Y cell death: a focus on mitochondrial quality control
Recent advances in the pharmacological applications and liver toxicity of triptolide
Selenium nanoparticles coupling with Astragalus Polysaccharides exert their cytotoxicities in MCF-7 cells by inhibiting autophagy and promoting apoptosis
A pivotal role of selective autophagy in mitochondrial quality control: Implications for zinc oxide nanoparticles induced neurotoxicity
Inhibitory activity and mechanism of calycosin and calycosin-7-O-β-D-glucoside on α-glucosidase: Spectroscopic and molecular docking analyses
Triptolide and methotrexate binding competitively to bovine serum albumin: A study of spectroscopic experiments, molecular docking, and molecular dynamic simulation
Farrerol Directly Targets GSK-3<i>β</i> to Activate Nrf2-ARE Pathway and Protect EA.hy926 Cells against Oxidative Stress-Induced Injuries
<i>Astragalus membranaceus</i>Injection Suppresses Production of Interleukin-6 by Activating Autophagy through the AMPK-mTOR Pathway in Lipopolysaccharide-Stimulated Macrophages
Synthesis, characterization and antitumor properties of selenium nanoparticles coupling with ferulic acid
Synthesis and cytotoxic activities of novel 4-methoxy-substituted and 5-methyl-substituted (3&prime;<em>S</em>,4&prime;<em>S</em>)-(-)-<em>cis</em>-khellactone derivatives that induce apoptosis via the intrinsic pathway
Chitosan attenuates dibutyltin-induced apoptosis in PC12 cells through inhibition of the mitochondria-dependent pathway
Diorganotin (IV) complexes with 4-nitro-N-phthaloyl-glycine: Synthesis, characterization, antitumor activity and DNA-binding studies
Design, Synthesis and Antitumor Activity of Novel 4-Methyl-(3'S,4'S)-cis-khellactone Derivatives