Area of research
Genetics · Molecular Biology
Research interest
Research focused on Chromatin and Senescence, with related work in Phenotype, Heterochromatin, Cohesin. Notable publications include 'Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation', 'Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence', and 'Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53'.
Author Correction: Titration of RAS alters senescent state and influences tumour initiation
Titration of RAS alters senescent state and influences tumour initiation
HMGA1 orchestrates chromatin compartmentalization and sequesters genes into 3D networks coordinating senescence heterogeneity
Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis
HMGA1 orchestrates chromatin compartmentalization and sequesters genes into 3D networks coordinating senescence heterogeneity
Abstract A039: Oncogenic Ras Dosage Alters Senescent Immune Response and Influences Tumour Initiation
Abstract PR-09: Oncogenic Ras Dosage Alters Senescent Immune Response and Influences Tumour Initiation
Titration of oncogenic RAS alters senescent state and influences tumour initiation
The Chromatin Regulator HMGA1a Undergoes Phase Separation in the Nucleus**
Core–Shell Spheroid‐Laden Microgels Crosslinked under Biocompatible Conditions for Probing Cancer‐Stromal Communication
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence
The chromatin regulator HMGA1a undergoes phase separation in the nucleus
Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence
Transcription-driven cohesin repositioning rewires chromatin loops in cellular senescence
Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53
Normalization of metabolomics data with applications to correlation maps
Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation
Cell Senescence as Both a Dynamic and a Static Phenotype