Area of research
Immunology · Pathology and Forensic Medicine
Research interest
Research interests include T-cell and B-cell Immunology, Immune Cell Function and Interaction, Immunodeficiency and Autoimmune Disorders, and Lymphoma Diagnosis and Treatment.
Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease
Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome
Germline mutations in the transcription factor IKZF5 cause thrombocytopenia
Variation in PU.1 binding and chromatin looping at neutrophil enhancers influences autoimmune disease susceptibility
Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia
Platelet function is modified by common sequence variation in megakaryocyte super enhancers
Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
Transcriptional diversity during lineage commitment of human blood progenitors