Area of research
Molecular Biology · Public Health, Environmental and Occupational Health
Research interest
Research interests include Phosphodiesterase function and regulation, Reproductive Biology and Fertility, Receptor Mechanisms and Signaling, and Cholinesterase and Neurodegenerative Diseases.
Molecular and genetic insights into human ovarian aging from single-nuclei multi-omics analyses
A genome-wide perspective of the maternal mRNA translation program during oocyte development
Alternative cleavage and polyadenylation of the Ccnb1 mRNA defines accumulation of cyclin protein during the meiotic cell cycle
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases
Genome-wide analysis reveals a switch in the translational program upon oocyte meiotic resumption
The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation
Cyclin B2 is required for progression through meiosis in mouse oocytes
Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events
Functional selectivity of GPCR-directed drug action through location bias
International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases
The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle
DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation
Dynamic secretion during meiotic reentry integrates the function of the oocyte and cumulus cells
A CaMKII/PDE4D negative feedback regulates cAMP signaling
Hira-Mediated H3.3 Incorporation Is Required for DNA Replication and Ribosomal RNA Transcription in the Mouse Zygote
Multiple Pathways Mediate Luteinizing Hormone Regulation of cGMP Signaling in the Mouse Ovarian Follicle1
Mice deficient in phosphodiesterase-4A display anxiogenic-like behavior
Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytes
PDE4 as a target for cognition enhancement
Cyclic AMP compartments and signaling specificity: Role of cyclic nucleotide phosphodiesterases
Cyclic Adenosine Monophosphate Phosphodiesterase Type 4 Protects Against Atrial Arrhythmias
Phosphoinositide 3-Kinase γ Protects Against Catecholamine-Induced Ventricular Arrhythmia Through Protein Kinase A–Mediated Regulation of Distinct Phosphodiesterases
A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type
Amphiregulin promotes the maturation of oocytes isolated from the small antral follicles of the rhesus macaque