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James Uphill

Wellcome Sanger Institute · GB
Area of research
Neurology · Molecular Biology
Research interest
Research interests include Prion Diseases and Protein Misfolding, Neurological diseases and metabolism, Alzheimer's disease research and treatments, and Amyotrophic Lateral Sclerosis Research.
h-index
32
citations
12,604
works
63
NIH funding
primary concept
email

Recent publications

Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood
Biological Psychiatry 2022cited by 49position: middledoi
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study
The Lancet Neurology 2020cited by 76position: middledoi
Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis
Scientific Reports 2020cited by 10position: middledoi
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Nature Genetics 2019cited by 3,176position: middledoi
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Nature Genetics 2019cited by 90position: middledoi
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia
Scientific Reports 2019cited by 16position: middledoi
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
Nature Medicine 2018cited by 155position: middledoi
CXCR4 involvement in neurodegenerative diseases
Translational Psychiatry 2018cited by 98position: middledoi
Author Correction: Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS
Scientific Reports 2018cited by 2position: middledoi
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS
Scientific Reports 2017cited by 44position: middledoi
Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease
Alzheimer s & Dementia 2016cited by 129position: middledoi
Frontotemporal dementia and its subtypes: a genome-wide association study
The Lancet Neurology 2014cited by 401position: middledoi
<i>R47H TREM2</i> variant increases risk of typical early‐onset Alzheimer's disease but not of prion or frontotemporal dementia
Alzheimer s & Dementia 2014cited by 116position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

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