Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Ion channel regulation and function, Neuroscience and Neuropharmacology Research, Cancer Immunotherapy and Biomarkers, and SARS-CoV-2 and COVID-19 Research.
Multifunctional NIR‐Triggered Nanozyme‐Based Microneedles for Synergistic Eradication of MRSA and Enhanced Wound Healing
PDLIM4 drives gastric cancer malignant progression and cisplatin resistance by inhibiting HSP70 ubiquitination and degradation via competitive interaction with STUB1
Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles.
Development of Broad-Spectrum Nanobodies for the Therapy and Diagnosis of SARS-CoV-2 and Its Multiple Variants
Innovative Dual mRNA-Lipid Nanoparticle Therapy Targeting CRHBP and CFHR3 for Enhanced Treatment of Hepatocellular Carcinoma
Disrupting the phase separation of KAT8–IRF1 diminishes PD-L1 expression and promotes antitumor immunity
Curcumin activates NLRC4, AIM2, and IFI16 inflammasomes and induces pyroptosis by up-regulated ISG3 transcript factor in acute myeloid leukemia cell lines
Bestrophin-2 and glutamine synthetase form a complex for glutamate release
Preparation of chitooligosaccharides with a low degree of polymerization and anti-microbial properties using the novel chitosanase AqCsn1
Dysregulated adaptive immune response contributes to severe COVID-19
PPM1G restricts innate immune signaling mediated by STING and MAVS and is hijacked by KSHV for immune evasion.
A network of phosphatidylinositol 4,5-bisphosphate binding sites regulates gating of the Ca <sup>2+</sup> -activated Cl <sup>−</sup> channel ANO1 (TMEM16A)
Anoctamin 5/TMEM16E facilitates muscle precursor cell fusion
Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation
Lipids and ions traverse the membrane by the same physical pathway in the nhTMEM16 scramblase
Identification of a lipid scrambling domain in ANO6/TMEM16F
The Ca<sup>2+</sup>‐activated Cl<sup>−</sup> channel, ANO1 (TMEM16A), is a double‐edged sword in cell proliferation and tumorigenesis
Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin
Characterization of Cardiac Anoctamin1 Ca<sup>2+</sup>‐Activated Chloride Channels and Functional Role in Ischemia‐Induced Arrhythmias
MONNA, a Potent and Selective Blocker for Transmembrane Protein with Unknown Function 16/Anoctamin-1
Activity-dependent regulation of dendritic growth and maintenance by glycogen synthase kinase 3β
Differential effects of Best disease causing missense mutations on bestrophin-1 trafficking
Explaining Calcium-Dependent Gating of Anoctamin-1 Chloride Channels Requires a Revised Topology