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Mark G. Frattini

Roswell Park Comprehensive Cancer Center · US
Area of research
Hematology · Oncology
Research interest
Research interests include Acute Myeloid Leukemia Research, Chronic Myeloid Leukemia Treatments, CAR-T cell therapy research, and Acute Lymphoblastic Leukemia research.
h-index
35
citations
11,375
works
154
NIH funding
primary concept
Medicine
email

Recent publications

Preliminary Results of Nathali-01: A First-in-Human Phase I/IIa Study of UCART20x22, a Dual Allogeneic CAR-T Cell Product Targeting CD20 and CD22, in Relapsed or Refractory (R/R) Non-Hodgkin Lymphoma (NHL)
Blood 2023cited by 15position: middledoi
Updated Results of the Phase I BALLI-01 Trial of UCART22 Process 2 (P2), an Anti-CD22 Allogeneic CAR-T Cell Product Manufactured By Cellectis Biologics, in Patients with Relapsed or Refractory (R/R) CD22+ B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Blood 2023cited by 14position: middledoi
Ameli-01: A Phase I Trial of UCART123v1.2, an Anti-CD123 Allogeneic CAR-T Cell Product, in Adult Patients with Relapsed or Refractory (R/R) CD123+ Acute Myeloid Leukemia (AML)
Blood 2022cited by 62position: middledoi
A phase 1 study of IDH305 in patients with IDH1R132-mutant acute myeloid leukemia or myelodysplastic syndrome
Journal of Cancer Research and Clinical Oncology 2022cited by 32position: middledoi
Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial
The Lancet Oncology 2021cited by 190position: middledoi
Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study
Blood 2020cited by 232position: middledoi
Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial
The Lancet Haematology 2020cited by 105position: middledoi
Effect of enasidenib (ENA) plus azacitidine (AZA) on complete remission and overall response versus AZA monotherapy in mutant<i>-IDH2</i> (<i>mIDH2</i>) newly diagnosed acute myeloid leukemia (ND-AML).
Journal of Clinical Oncology 2020cited by 37position: middledoi
Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia
Leukemia 2019cited by 250position: middledoi
Enasidenib Plus Azacitidine Significantly Improves Complete Remission and Overall Response Compared with Azacitidine Alone in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) with Isocitrate Dehydrogenase 2 (IDH2) Mutations: Interim Phase II Results from an Ongoing, Randomized Study
Blood 2019cited by 45position: middledoi
Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study
The Lancet Oncology 2018cited by 707position: middledoi
Phase 2 trial of a multivalent WT1 peptide vaccine (galinpepimut-S) in acute myeloid leukemia
Blood Advances 2018cited by 159position: middledoi
Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia
Leukemia 2018cited by 47position: middledoi
Results of a phase 1b study of venetoclax plus decitabine or azacitidine in untreated acute myeloid leukemia patients ≥ 65 years ineligible for standard induction therapy.
Journal of Clinical Oncology 2016cited by 49position: middledoi
A Phase 1b Study of Venetoclax (ABT-199/GDC-0199) in Combination with Decitabine or Azacitidine in Treatment-Naive Patients with Acute Myelogenous Leukemia Who Are ≥ to 65 Years and Not Eligible for Standard Induction Therapy
Blood 2015cited by 61position: middledoi
Relative Mitochondrial Priming of Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML
Cell 2012cited by 338position: middledoi
Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITD AML
Blood 2012cited by 172position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Courtney D. DiNardo · The University of Texas MD Anderson Cancer Center9 papers (2015–2022)Hagop M. Kantarjian · The University of Texas MD Anderson Cancer Center8 papers (2015–2021)Andrew H. Wei · CSL (Australia)6 papers (2016–2022)Stéphane de Botton · Université de Lille5 papers (2019–2021)Daniel A. Pollyea · University of Colorado Boulder5 papers (2015–2020)Eytan M. Stein · The University of Texas MD Anderson Cancer Center5 papers (2019–2021)Amir T. Fathi · University of Southern California4 papers (2019–2021)Anthony Letai · Harvard University4 papers (2012–2018)Keith W. Pratz · Abramson Cancer Center4 papers (2012–2018)Mack Mabry · AbbVie (United States)3 papers (2015–2018)Martin S. Tallman · Midwestern University3 papers (2018–2020)Andre C. Schuh · Princess Margaret Cancer Centre3 papers (2019–2021)Marina Konopleva · Anderson University - South Carolina3 papers (2015–2018)Michael J. Thirman · University of Chicago Medical Center3 papers (2015–2018)Frederik Lersch · Bristol-Myers Squibb (Switzerland)3 papers (2019–2021)Jing Gong · Sichuan University3 papers (2019–2021)Rod Humerickhouse · AbbVie (United States)3 papers (2015–2018)Kyle J. MacBeth · Bristol-Myers Squibb (Sweden)3 papers (2019–2020)Amer M. Zeidan · Yale Cancer Center3 papers (2019–2021)Brian A. Jonas · Cellular Therapeutics (United Kingdom)3 papers (2015–2018)