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Leon J. Thal

Oregon Health & Science University · US
Area of research
Psychiatry and Mental health · Physiology
Research interest
Research interests include Dementia and Cognitive Impairment Research, Alzheimer's disease research and treatments, Cholinesterase and Neurodegenerative Diseases, and Neuroscience and Neuropharmacology Research.
h-index
89
citations
41,173
works
331
NIH funding
primary concept
email

Recent publications

A novel spatiotemporal graph convolutional network framework for functional connectivity biomarkers identification of Alzheimer’s disease
Alzheimer s Research & Therapy 2024cited by 17position: middledoi
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction
Communications Medicine 2023cited by 69position: middledoi
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease
Nature Aging 2022cited by 46position: middledoi
The trend of disruption in the functional brain network topology of Alzheimer’s disease
Scientific Reports 2022cited by 40position: middledoi
Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology
Scientific Reports 2020cited by 134position: middledoi
Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
Nature Communications 2019cited by 123position: middledoi
The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
Nature Communications 2019cited by 114position: middledoi
Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics
Scientific Reports 2019cited by 93position: middledoi
A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data
Scientific Reports 2019cited by 26position: middledoi
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis
Proceedings of the National Academy of Sciences 2018cited by 103position: middledoi
Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
Nature Communications 2016cited by 1,179position: middledoi
Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
Nature Communications 2016cited by 344position: middledoi
Bayesian model reveals latent atrophy factors with dissociable cognitive trajectories in Alzheimer’s disease
Proceedings of the National Academy of Sciences 2016cited by 190position: middledoi
Morphometricity as a measure of the neuroanatomical signature of a trait
Proceedings of the National Academy of Sciences 2016cited by 71position: middledoi
Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE
Nature Communications 2015cited by 325position: middledoi
Large-scale genomics unveil polygenic architecture of human cortical surface area
Nature Communications 2015cited by 36position: middledoi

Grants

Effects of Nerve Growth Factor on Nucleus Basalis Magnocellularis Cholinergic Cell Recovery and Function
NSF9010252$270,0001990–1993PIRePORTER

Frequent collaborators

No co-authors indexed yet.