Area of research
Cardiology and Cardiovascular Medicine · Epidemiology
Research interest
Research focused on Troponin C and Troponin, with related work in Troponin complex, Allosteric regulation, Troponin T. Notable publications include 'The intrinsically disordered C terminus of troponin T binds to troponin C to modulate myocardial force generation', 'Clinical and Biophysical Characterization of a Mutation in the N-Helix Region of Cardiac Troponin C: Evidence for an Allosteric Mechanism of Contractile Dysfunction', and 'A Novel DCM-Associated Mutation in the N-Helix of Cardiac Troponin C Exhibits Impaired Contractile Kinetics and Reduced Ca 2+ -Sensitivity In Vitro'.