Area of research
Rheumatology · Immunology
Research interest
Research focused on Genome-wide association study and Immunology, with related work in Lupus nephritis, Genetics, Autoantibody. Notable publications include 'End‐Stage Renal Disease in African Americans With Lupus Nephritis Is Associated With APOL1', 'High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry', and 'Complement genes contribute sex-biased vulnerability in diverse disorders'.
Association between systemic lupus erythematosus and myasthenia gravis: A population-based National Study
Global discovery of lupus genetic risk variant allelic enhancer activity
Lupus Susceptibility Region Containing <i>CDKN1B</i> rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis
Complement genes contribute sex-biased vulnerability in diverse disorders
Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus
Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians
Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen
Genetic influences on susceptibility to rheumatoid arthritis in African-Americans
Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks
Brief Report: Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome
High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification
Heightened preclinical dysregulation of distinct adaptive and renal-associated mediators in patients who develop nephritis as they transition to systemic lupus erythematosus classification
X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome
Identification of a Systemic Lupus Erythematosus Risk Locus Spanning <i>ATG16L2, FCHSD2</i>, and <i>P2RY2</i> in Koreans
Lupus risk variants in the PXK locus alter B-cell receptor internalization
Lupus Nephritis Susceptibility Loci in Women with Systemic Lupus Erythematosus
MHC associations with clinical and autoantibody manifestations in European SLE
Two Functional Lupus-Associated BLK Promoter Variants Control Cell-Type- and Developmental-Stage-Specific Transcription
End‐Stage Renal Disease in African Americans With Lupus Nephritis Is Associated With <i>APOL1</i>
Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production
Brief Report: Large‐scale analysis of tumor necrosis factor α levels in systemic lupus erythematosus