Area of research
Molecular Biology · Neurology
Research interest
Research focused on Neuroscience and TREM2, with related work in Microglia, Neurodegeneration, Transient receptor potential channel. Notable publications include 'Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology', 'The Pattern of Cortical Dysfunction in a Mouse Model of a Schizophrenia-Related Microdeletion', and 'Behavioral characterization of a CRISPR-generated TRPA1 knockout rat in models of pain, itch, and asthma'.
Neutral or Detrimental Effects of TREM2 Agonist Antibodies in Preclinical Models of Alzheimer’s Disease and Multiple Sclerosis
Nav1.7 is essential for nociceptor action potentials in the mouse in a manner independent of endogenous opioids
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury
Genetic ablation of Gpnmb does not alter synuclein-related pathology
Behavioral characterization of a CRISPR-generated TRPA1 knockout rat in models of pain, itch, and asthma
The Pattern of Cortical Dysfunction in a Mouse Model of a Schizophrenia-Related Microdeletion