Area of research
Organic Chemistry · Biomedical Engineering
Research interest
Research interests include 3D Printing in Biomedical Research, Cellular Mechanics and Interactions, Hydrogels: synthesis, properties, applications, and Advanced Polymer Synthesis and Characterization.
Y chromosome–linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues
Engineered epithelial curvature controls Paneth cell localization in intestinal organoids
Light-based vat-polymerization bioprinting
Substrate stiffness modulates cardiac fibroblast activation, senescence and proinflammatory secretory phenotype
Thermal Stabilization of Biologics with Photoresponsive Hydrogels
Immunofunctional photodegradable poly(ethylene glycol) hydrogel surfaces for the capture and release of rare cells
Mechanobiology of the heart valve interstitial cell: Simulation, experiment, and discovery
Hydrogels with Reversible Mechanics to Probe Dynamic Cell Microenvironments
Clickable Microgel Scaffolds as Platforms for 3D Cell Encapsulation
Amplified Photodegradation of Cell‐Laden Hydrogels via an Addition–Fragmentation Chain Transfer Reaction
Myofibroblastic activation of valvular interstitial cells is modulated by spatial variations in matrix elasticity and its organization
Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel Promotes Cardiomyocytes Survival and Maturation
Synthesis of Microgel Sensors for Spatial and Temporal Monitoring of Protease Activity
Dynamic Changes in Material Properties and Degradation of Poly(ethylene glycol)–Hydrazone Gels as a Function of pH
Hydrogels with Reversible Mechanics to Probe Dynamic Cell Microenvironments
The design of reversible hydrogels to capture extracellular matrix dynamics
Spatially patterned matrix elasticity directs stem cell fate
Bio-inspired 3D microenvironments: a new dimension in tissue engineering
Enhanced user-control of small molecule drug release from a poly(ethylene glycol) hydrogel via azobenzene/cyclodextrin complex tethers
Three-Dimensional High-Throughput Cell Encapsulation Platform to Study Changes in Cell-Matrix Interactions
PEG–peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity
Progress in material design for biomedical applications
Dynamic stiffening of poly(ethylene glycol)-based hydrogels to direct valvular interstitial cell phenotype in a three-dimensional environment
Measuring dynamic cell–material interactions and remodeling during 3D human mesenchymal stem cell migration in hydrogels
Photoresponsive Elastic Properties of Azobenzene-Containing Poly(ethylene-glycol)-Based Hydrogels
Synthetic Mimics of the Extracellular Matrix: How Simple is Complex Enough?
Development of a Cellularly Degradable PEG Hydrogel to Promote Articular Cartilage Extracellular Matrix Deposition
Microarray analyses to quantify advantages of 2D and 3D hydrogel culture systems in maintaining the native valvular interstitial cell phenotype
Thiol-ene and photo-cleavage chemistry for controlled presentation of biomolecules in hydrogels
In vitro model alveoli from photodegradable microsphere templates
RECODE: Materials-directed differentiation of intestinal organoids of uniform size and shape
Dynamic and Reversible Control over Biological Signals in Hydrogel Matrices
Rheological Characterization of Cellularly Remodeled Hydrogel Matrices
Spatiotemporal Regulated Click Hydrogels for 3D Cell Culture
National Science Foundation Alan T. Waterman Award
CUBE: Integrating Biological Engineering into Undergraduate Engineering Education at CU
CAREER: Photocrosslinkable Polymers for Fracture Fixation
SGER: Development of Photocurable Degradable Polymers for Orthopedic Applications