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Amy M. Pooler

Sangamo BioSciences (United States) · US
Area of research
Physiology · Cellular and Molecular Neuroscience
Research interest
Research interests include Alzheimer's disease research and treatments, Neuroscience and Neuropharmacology Research, Neuroinflammation and Neurodegeneration Mechanisms, and Cholinesterase and Neurodegenerative Diseases.
h-index
26
citations
3,335
works
42
NIH funding
primary concept
email

Recent publications

Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures
Cell Death and Disease 2017cited by 65position: middledoi
Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease
Acta Neuropathologica Communications 2016cited by 91position: middledoi
Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer’s Disease
Molecular Neurobiology 2016cited by 69position: middledoi
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease
Acta Neuropathologica Communications 2015cited by 233position: firstdoi
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity
The EMBO Journal 2015cited by 129position: middledoi
Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons
Neurobiology of Disease 2015cited by 73position: middledoi
Intracellular and Extracellular Roles for Tau in Neurodegenerative Disease
Journal of Alzheimer s Disease 2014cited by 62position: middledoi
Physiological release of endogenous tau is stimulated by neuronal activity
EMBO Reports 2013cited by 663position: firstdoi
A role for tau at the synapse in Alzheimer's disease pathogenesis
Neuropharmacology 2013cited by 208position: firstdoi
Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targets
Alzheimer s Research & Therapy 2013cited by 123position: firstdoi
Studying synapses in human brain with array tomography and electron microscopy
Nature Protocols 2013cited by 121position: middledoi
Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model
Acta Neuropathologica 2013cited by 116position: middledoi
NUB1 modulation of GSK3β reduces tau aggregation
Human Molecular Genetics 2012cited by 34position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Diane P. Hanger · King's College London7 papers (2012–2017)Tara L. Spires‐Jones · University of Edinburgh6 papers (2013–2016)Wendy Noble · King's College London5 papers (2013–2017)Bradley T. Hyman · Harvard University5 papers (2013–2015)Dawn H. W. Lau · King's College London4 papers (2013–2016)Emma Claire Phillips · NHS Lothian4 papers (2013–2017)Samantha B. Nicholls · University of Massachusetts Amherst4 papers (2013–2015)Susanne Wegmann · Max Delbrück Center3 papers (2013–2015) · 3 papers (2013–2015) · 3 papers (2013–2015)George A. Carlson · Hennepin Healthcare Research Institute3 papers (2013–2015)Christopher William · New York University2 papers (2015–2015) · 2 papers (2015–2015) · 2 papers (2015–2015)Eduardo A. Maury · Massachusetts General Hospital2 papers (2015–2015)Ksenia Kurbatskaya · University of Southampton1 papers (2017–2017) · 1 papers (2015–2015)Ann K. Wright · University of Edinburgh1 papers (2013–2013)Matthew P. Frosch · Harvard University1 papers (2013–2013)Matthew Wade · Université Laval1 papers (2017–2017)