Area of research
Hematology · Genetics
Research interest
Research interests include Acute Myeloid Leukemia Research, Chronic Myeloid Leukemia Treatments, Chronic Lymphocytic Leukemia Research, and Acute Lymphoblastic Leukemia research.
A translational protocol optimizes the isolation of plasma-derived extracellular vesicle proteomics
Preanalytical framework for routine clinical use of liquid biopsies: combining EVs and cfDNA
Targeting tumoral heterogeneity in lung cancer: a novel, CT-texture-guided targeted biopsy approach with exome sequencing
Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis: A retrospective analysis of the DRST and GREM registries
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
Therapy resistance mechanisms in hematological malignancies
3019 – SINGLE-CELL PROTEO-GENOMIC REFERENCE MAPS OF THE HEMATOPOIETIC SYSTEM ENABLE THE PURIFICATION AND MASSIVE PROFILING OF PRECISELY DEFINED CELL STATES
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics
Genome-wide association study identifies susceptibility loci for acute myeloid leukemia
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states
Molecular and phenotypic diversity of <I>CBL</I>-mutated juvenile myelomonocytic leukemia
KIT D816 mutated/CBF-negative acute myeloid leukemia: a poor-risk subtype associated with systemic mastocytosis
Discontinuation of tyrosine kinase inhibitor therapy in chronic myeloid leukaemia (EURO-SKI): a prespecified interim analysis of a prospective, multicentre, non-randomised, trial
Genomic CDKN2A/2B deletions in adult Ph+ ALL are adverse despite allogeneic stem cell transplantation
Incidence and prognostic impact of cytogenetic aberrations in patients with systemic mastocytosis
Enhanced labile plasma iron and outcome in acute myeloid leukaemia and myelodysplastic syndrome after allogeneic haemopoietic cell transplantation (ALLIVE): a prospective, multicentre, observational trial
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics
Human haematopoietic stem cell lineage commitment is a continuous process
Proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions
Infectious complications in patients with myelodysplastic syndromes: A review of the literature with emphasis on patients treated with 5‐azacitidine
Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure
Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia
Impact of unbalanced minor route versus major route karyotypes at diagnosis on prognosis of CML
A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition
Myelodysplastic Cells in Patients Reprogram Mesenchymal Stromal Cells to Establish a Transplantable Stem Cell Niche Disease Unit
Mesenchymal and MDS stem cells shape an interactive disease unit in the bone marrow
Development of a DNA-Based Targeted Assay Suitable for Accurate Quantification of Chromosomal Deletions in Myelodysplastic Syndromes with Deletion (5q) and Other Clonal Diseases
Quantitative Analysis of Patient-Specific Lesions in Primary and Xenografted Myelodysplastic Syndromes Reveals Complex Hierarchies and Subclonal Diversity That Evolve during Disease Progression
Molecular Alterations in Bone Marrow Mesenchymal Stroma Cells of AML Patients