Area of research
Biomedical Engineering · Cell Biology
Research interest
Research interests include 3D Printing in Biomedical Research, Cellular Mechanics and Interactions, Cancer Cells and Metastasis, and Angiogenesis and VEGF in Cancer.
Mechanobiology of the blood-brain barrier during development, disease and ageing
Long-term physiological flow rescues regressed microvascular networks and increases their longevity
Deep and Dynamic Metabolic and Structural Imaging in Living Tissues
Linking cell mechanical memory and cancer metastasis
Modeling early pathophysiological phenotypes of diabetic retinopathy in a human inner blood-retinal barrier-on-a-chip
Patient-specific vascularized tumor model: Blocking monocyte recruitment with multispecific antibodies targeting CCR2 and CSF-1R
Engineered 3D human neurovascular model of Alzheimer's disease to study vascular dysfunction
Personalized Vascularized Models of Breast Cancer Desmoplasia Reveal Biomechanical Determinants of Drug Delivery to the Tumor
Challenges and Future Perspectives in Modeling Neurodegenerative Diseases Using Organ‐on‐a‐Chip Technology
Engineering microvascular networks using a KLF2 reporter to probe flow-dependent endothelial cell function
Sensing and guiding cell-state transitions by using genetically encoded endoribonuclease-mediated microRNA sensors
Deep and dynamic metabolic and structural imaging in living tissues
Ether lipids influence cancer cell fate by modulating iron uptake
VONet: A deep learning network for 3D reconstruction of organoid structures with a minimal number of confocal images
Utilizing convolutional neural networks for discriminating cancer and stromal cells in three-dimensional cell culture images with nuclei counterstain
Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage
Development of a perfusable, hierarchical microvasculature-on-a-chip model
Emergent mechanical control of vascular morphogenesis
Endothelium and Subendothelial Matrix Mechanics Modulate Cancer Cell Transendothelial Migration
Accelerating the in vitro emulation of Alzheimer’s disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model
Stabilization and improved functionality of three-dimensional perfusable microvascular networks in microfluidic devices under macromolecular crowding
Priming a vascular-selective cytokine response permits CD8+ T-cell entry into tumors
Engineered human blood–brain barrier microfluidic model for vascular permeability analyses
A predictive microfluidic model of human glioblastoma to assess trafficking of blood–brain barrier-penetrant nanoparticles
Progress in multicellular human cardiac organoids for clinical applications
Interstitial Flow Promotes the Formation of Functional Microvascular Networks In Vitro through Upregulation of Matrix Metalloproteinase‐2
New Strategy for Promoting Vascularization in Tumor Spheroids in a Microfluidic Assay
A Robust Method for Perfusable Microvascular Network Formation In Vitro
Omentum-on-a-chip: A multicellular, vascularized microfluidic model of the human peritoneum for the study of ovarian cancer metastases
Principles for the design of multicellular engineered living systems
NSF Science and Technology Center: Emergent Behaviors of Integrated Cellular Systems
EFRI-CBE: A Multifaceted Approach to the Modeling of Angiogenesis
Travel Request: Summit of Experts in Biomechanics
U.S.-Korea Cooperative Research on Computational Fluid Dynamics for the Design and Optimization of Cardiac Assist Devices
A Broad Program of Research on Flexible -Walled Tubes