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Ryan M. Roth

University of Illinois Chicago · US
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Area of research
Artificial Intelligence · Electrical and Electronic Engineering
Research interest
Research focused on Antithrombin and Allosteric regulation, with related work in Heparin, Protease, Serpin. Notable publications include 'Conformational Activation of Antithrombin by Heparin Involves an Altered Exosite Interaction with Protease', 'Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully...', and 'Paramount Importance of Core Conformational Changes for Heparin Allosteric Activation of Antithrombin'.
h-index
citations
96
works
4
NIH funding
primary concept
email

Recent publications

Paramount Importance of Core Conformational Changes for Heparin Allosteric Activation of Antithrombin
Biochemistry 2021cited by 15position: middledoi
Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States
Journal of Biological Chemistry 2015cited by 20position: firstdoi
Conformational Activation of Antithrombin by Heparin Involves an Altered Exosite Interaction with Protease
Journal of Biological Chemistry 2014cited by 46position: middledoi
The Allosteric Mechanism of Activation of Antithrombin as an Inhibitor of Factor IXa and Factor Xa
Journal of Biological Chemistry 2013cited by 15position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Peter G.W. Gettins · University of Illinois Chicago4 papers (2013–2021)Gonzalo Izaguirre · University of Illinois Chicago4 papers (2013–2021)Steven T. Olson · University of Illinois Chicago4 papers (2013–2021)Richard Swanson · University of Illinois Chicago4 papers (2013–2021)Alireza R. Rezaie · University of Oklahoma Health Sciences Center1 papers (2014–2014)Alexey Dementiev · University of Illinois Chicago1 papers (2013–2013)Sonia Águila · Royal College of Surgeons in Ireland1 papers (2014–2014)Giulia Isetti · University of Illinois Chicago1 papers (2013–2013)Lixin Qi · Wenzhou Medical University1 papers (2014–2014)Susan Bock · University of Utah1 papers (2015–2015)
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