Area of research
Public Health, Environmental and Occupational Health · Infectious Diseases
Research interest
Research focused on Streptococcus pyogenes and Virulence, with related work in Streptococcus, Serotype, Cytolysin. Notable publications include 'Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus', 'The Globally Disseminated M1T1 Clone of Group A Streptococcus Evades Autophagy for Intracellular Replication', and 'The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity'.
All major cholesterol-dependent cytolysins use glycans as cellular receptors
Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models
Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus
The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity
The Globally Disseminated M1T1 Clone of Group A Streptococcus Evades Autophagy for Intracellular Replication
Streptococcal collagen‐like protein A and general stress protein 24 are immunomodulating virulence factors of group A <i>Streptococcus</i>
Conserved anchorless surface proteins as group A streptococcal vaccine candidates
Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone
Streptokinase variants from <i><scp>S</scp>treptococcus pyogenes</i> isolates display altered plasminogen activation characteristics – implications for pathogenesis