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Martin Löwer

Johannes Gutenberg University Mainz · DE
Area of research
Immunology · Oncology
Research interest
Research interests include Immunotherapy and Immune Responses, vaccines and immunoinformatics approaches, Cancer Immunotherapy and Biomarkers, and CAR-T cell therapy research.
h-index
30
citations
9,907
works
96
NIH funding
primary concept
Medicine
email

Recent publications

Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial
Nature Medicine 2025cited by 89position: middledoi
MC38 colorectal tumor cell lines from two different sources display substantial differences in transcriptome, mutanome and neoantigen expression
Frontiers in Immunology 2023cited by 22position: middledoi
CoVigator—A Knowledge Base for Navigating SARS-CoV-2 Genomic Variants
Viruses 2023cited by 6position: middledoi
Identification of neoantigens for individualized therapeutic cancer vaccines
Nature Reviews Drug Discovery 2022cited by 550position: middledoi
Accurate detection of tumor-specific gene fusions reveals strongly immunogenic personal neo-antigens
Nature Biotechnology 2022cited by 57position: middledoi
Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates
PLoS ONE 2021cited by 44position: middledoi
NeoFox: annotating neoantigen candidates with neoantigen features
Bioinformatics 2021cited by 23position: middledoi
A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors
Cancers 2021cited by 22position: middledoi
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
Cell 2020cited by 527position: middledoi
Multi-Omics Characterization of the 4T1 Murine Mammary Gland Tumor Model
Frontiers in Oncology 2020cited by 205position: lastdoi
Bioinformatics for Cancer Immunotherapy
Methods in molecular biology 2020cited by 63position: lastdoi
Integrative analysis of structural variations using short-reads and linked-reads yields highly specific and sensitive predictions
PLoS Computational Biology 2020cited by 8position: middledoi
A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies
bioRxiv (Cold Spring Harbor Laboratory) 2020cited by 2position: middledoi
Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma
Nature 2019cited by 15position: middledoi
Abstract CT221: Mutanome engineered RNA immuno-therapy (MERIT) for patients with triple negative breast cancer (TNBC)
Cancer Research 2019cited by 3position: middledoi
Abstract CT221: Mutanome engineered RNA immuno-therapy (MERIT) for patients with triple negative breast cancer (TNBC)
Clinical Trials 2019cited by 2position: middledoi
Actively personalized vaccination trial for newly diagnosed glioblastoma
Nature 2018cited by 922position: middledoi
Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3′ UTRs Identified by Cellular Library Screening
Molecular Therapy 2018cited by 353position: middledoi
HLA and proteasome expression body map
BMC Medical Genomics 2018cited by 113position: middledoi
Challenges towards the realization of individualized cancer vaccines
Nature Biomedical Engineering 2018cited by 47position: middledoi
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
Nature 2017cited by 2,430position: middledoi
Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis
Cancer Cell 2017cited by 349position: middledoi
Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution
Nature Communications 2017cited by 314position: middledoi
IVAC MUTANOME: A first-in-human phase I clinical trial targeting individual mutant neoantigens for the treatment of melanoma
Annals of Oncology 2017cited by 15position: middledoi
Abstract A110: Mutant MHC class II epitopes drive therapeutic immune responses to cancer
Cancer Immunology Research 2016cited by 13position: middledoi
Mutant MHC class II epitopes drive therapeutic immune responses to cancer
Nature 2015cited by 1,237position: middledoi
Mutanome Engineered RNA Immunotherapy: Towards Patient-Centered Tumor Vaccination
Journal of Immunology Research 2015cited by 41position: middledoi
Tick Salivary Sialostatin L Represses the Initiation of Immune Responses by Targeting IRF4-Dependent Transcription in Murine Mast Cells
The Journal of Immunology 2015cited by 33position: middledoi
In Silico HLA Typing Using Standard RNA-Seq Sequence Reads
Methods in molecular biology 2015cited by 17position: middledoi
Abstract CT202: IVAC MUTANOME: Individualized vaccines for the treatment of cancer
Cancer Research 2015cited by 4position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Uğur Şahin · Technical University of Munich24 papers (2012–2023)Özlem Türeci · Helmholtz Institute for Translational Oncology Mainz12 papers (2012–2022)Barbara Schrörs · Johannes Gutenberg University Mainz11 papers (2015–2023)Sebastian Boegel · Johannes Gutenberg University Mainz9 papers (2012–2020)Mustafa Diken · Gutenberg College9 papers (2012–2023)John C. Castle · University Hospitals Sussex NHS Foundation Trust8 papers (2012–2018)Thomas Bukur · Johannes Gutenberg University Mainz7 papers (2012–2023)Sebastian Kreiter · Gutenberg College6 papers (2012–2019)Jos de Graaf · Johannes Gutenberg University Mainz5 papers (2012–2020)Andreas N. Kuhn · BioNTech (Germany)5 papers (2012–2019)Mathias Vormehr · BioNTech (Germany)5 papers (2015–2023)Valesca Bukur · Johannes Gutenberg University Mainz5 papers (2017–2020)Arbel D. Tadmor · BioNTech (Germany)4 papers (2015–2020)Patrick Sorn · Johannes Gutenberg University Mainz4 papers (2018–2023)Christoph Holtsträter · Johannes Gutenberg University Mainz4 papers (2020–2023)Franziska Lang · Johannes Gutenberg University Mainz4 papers (2021–2023)Stefanie Bolte · BioNTech (Germany)3 papers (2017–2019)Pablo Riesgo-Ferreiro · Institute of Bioinformatics3 papers (2021–2023)Niels van de Roemer · Johannes Gutenberg University Mainz3 papers (2012–2016)Evelyna Derhovanessian · BioNTech (Germany)3 papers (2017–2019)