Area of research
Molecular Biology · Reproductive Medicine
Research interest
Research focused on CRISPR and Computational biology, with related work in Genome editing, dbSNP, Induced pluripotent stem cell. Notable publications include 'Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity', 'A highly specific CRISPR-Cas12j nuclease enables allele-specific genome editing', and 'Base Editing Mediated Generation of Point Mutations Into Human Pluripotent Stem Cells for Modeling Disease'.
A highly specific CRISPR-Cas12j nuclease enables allele-specific genome editing
Prediction of base editor off-targets by deep learning
Closely related type II-C Cas9 orthologs recognize diverse PAMs
Identification of SaCas9 orthologs containing a conserved serine residue that determines simple NNGG PAM recognition
Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity
Efficient Correction of a Hypertrophic Cardiomyopathy Mutation by ABEmax-NG
Compact SchCas9 Recognizes the Simple NNGR PAM
Base Editing Mediated Generation of Point Mutations Into Human Pluripotent Stem Cells for Modeling Disease