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Christoph Laske

Korea University · KR
Area of research
Psychiatry and Mental health · Physiology
Research interest
Research interests include Dementia and Cognitive Impairment Research, Alzheimer's disease research and treatments, Functional Brain Connectivity Studies, and Advanced Neuroimaging Techniques and Applications.
h-index
57
citations
14,369
works
395
NIH funding
primary concept
email

Recent publications

Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia
Nature Medicine 2025cited by 21position: middledoi
Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease
Alzheimer s Research & Therapy 2025cited by 13position: middledoi
The landscape of autosomal-dominant Alzheimer’s disease: global distribution and age of onset
Brain 2025cited by 12position: middledoi
Blood biomarkers confirm subjective cognitive decline (SCD) as a distinct molecular and clinical stage within the NIA-AA framework of Alzheimer´s disease
Molecular Psychiatry 2025cited by 10position: middledoi
Cognitive reserve against Alzheimer’s pathology is linked to brain activity during memory formation
Nature Communications 2024cited by 35position: middledoi
Perivascular space enlargement accelerates in ageing and Alzheimer’s disease pathology: evidence from a three-year longitudinal multicentre study
Alzheimer s Research & Therapy 2024cited by 32position: middledoi
A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings
Brain 2024cited by 28position: middledoi
Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition
Molecular Psychiatry 2024cited by 26position: middledoi
Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease
Nature Communications 2024cited by 22position: middledoi
Amyloid and SCD jointly predict cognitive decline across Chinese and German cohorts
Alzheimer s & Dementia 2024cited by 13position: middledoi
Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects
Communications Medicine 2024cited by 9position: middledoi
Locus coeruleus signal intensity and emotion regulation in agitation in Alzheimer’s disease
Brain Communications 2024cited by 8position: middledoi
Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring 2024cited by 8position: middledoi
Short communication: Lifetime musical activity and resting-state functional connectivity in cognitive networks
PLoS ONE 2024cited by 6position: middledoi
Inferior Frontal Sulcal Hyperintensities on Brain MRI Are Associated with Amyloid Positivity beyond Age—Results from the Multicentre Observational DELCODE Study
Diagnostics 2024cited by 4position: middledoi
Reduced expression of fMRI subsequent memory effects with increasing severity across the Alzheimer’s disease risk spectrum
Imaging Neuroscience 2024cited by 3position: middledoi
Symptomatic Clusters Related to Amyloid Positivity in Cognitively Unimpaired Individuals
Journal of Alzheimer s Disease 2024cited by 2position: middledoi
A generalizable data‐driven model of atrophy heterogeneity and progression in a memory clinic setting
Alzheimer s & Dementia 2024cited by 1position: middledoi
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease
Nature Medicine 2023cited by 168position: middledoi
Altered limbic functional connectivity in individuals with subjective cognitive decline: Converging and diverging findings across Chinese and German cohorts
Alzheimer s & Dementia 2023cited by 25position: middledoi
Arterial hypertension and β-amyloid accumulation have spatially overlapping effects on posterior white matter hyperintensity volume: a cross-sectional study
Alzheimer s Research & Therapy 2023cited by 23position: middledoi
Brain reserve contributes to distinguishing preclinical Alzheimer’s stages 1 and 2
Alzheimer s Research & Therapy 2023cited by 14position: middledoi
Performance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia
Frontiers in Psychiatry 2023cited by 13position: middledoi
Machine learning‐based classification of Alzheimer's disease and its at‐risk states using personality traits, anxiety, and depression
International Journal of Geriatric Psychiatry 2023cited by 10position: middledoi
Cognitive Trajectories in Preclinical and Prodromal Alzheimer’s Disease Related to Amyloid Status and Brain Atrophy: A Bayesian Approach
Journal of Alzheimer s Disease Reports 2023cited by 5position: middledoi
Cortical Amyloid Burden Relates to Basal Forebrain Volume in Subjective Cognitive Decline
Journal of Alzheimer s Disease 2023cited by 5position: middledoi
A 6-items Questionnaire (6-QMD) captures a Mediterranean like dietary pattern and is associated with memory performance and hippocampal volume in elderly and persons at risk for Alzheimer’s disease
Nutrition and Healthy Aging 2023cited by 3position: middledoi
Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers
Acta Neuropathologica 2022cited by 135position: middledoi
Cholinergic white matter pathways along the Alzheimer's disease continuum
Brain 2022cited by 57position: middledoi
Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve
Frontiers in Psychology 2022cited by 22position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Jens Wiltfang · Johannes Gutenberg University Mainz2 papers (2019–2020)Annika Spottke · Technical University of Munich2 papers (2019–2020)Oliver Peters · German Center for Neurodegenerative Diseases2 papers (2019–2020)Stefan Teipel · German Center for Neurodegenerative Diseases2 papers (2019–2020)Katharina Büerger · Charité - Universitätsmedizin Berlin2 papers (2019–2020)Klaus Fließbach · University of Bonn2 papers (2019–2020)Josef Priller · Klinik und Poliklinik für Psychiatrie und Psychotherapie2 papers (2019–2020)Frank Jessen · University Hospital Cologne2 papers (2019–2020)Anja Schneider · University of Bonn2 papers (2019–2020)Siegmund Braun · Technical University of Munich1 papers (2015–2015)Tammie L.S. Benzinger · Cornell University1 papers (2017–2017)Emrah Düzel · University of Tübingen1 papers (2019–2019)Stephen Salloway · Brown University1 papers (2017–2017)James M. Noble · Allen Institute for Brain Science1 papers (2017–2017)Andreas Fellgiebel · New York University1 papers (2020–2020) · 1 papers (2019–2019)Maria Alevizaki · National and Kapodistrian University of Athens1 papers (2015–2015)Stefan Klöppel · Twitter (United States)1 papers (2020–2020)Adnan Kastrati · Deutsches Jugendinstitut1 papers (2015–2015)Efstathios Kastritis · Frontier Science Foundation-Hellas1 papers (2015–2015)