Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Protein Kinase Regulation and GTPase Signaling, Receptor Mechanisms and Signaling, and Cellular transport and secretion.
KRAS-dependent cancer cells promote survival by producing exosomes enriched in Survivin
SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis
Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation
Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.
The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy
Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells
Dibenzophenanthridines as Inhibitors of Glutaminase C and Cancer Cell Proliferation
Rho GTPases and their roles in cancer metabolism