Area of research
Spectroscopy · Molecular Biology
Research interest
Research interests include Mass Spectrometry Techniques and Applications, Protein Structure and Dynamics, Lipid Membrane Structure and Behavior, and Drug Transport and Resistance Mechanisms.
Linking function to global and local dynamics in an elevator-type transporter
Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB
Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry
Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome
Integrating hydrogen–deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins
Direct protein-lipid interactions shape the conformational landscape of secondary transporters
Interrogating Membrane Protein Conformational Dynamics within Native Lipid Compositions